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Self-defense: the fruit fly style.

作者信息

Medzhitov R, Janeway C A

机构信息

Section of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.

出版信息

Proc Natl Acad Sci U S A. 1998 Jan 20;95(2):429-30. doi: 10.1073/pnas.95.2.429.

DOI:10.1073/pnas.95.2.429
PMID:9435208
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC33794/
Abstract
摘要

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本文引用的文献

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Drosophila immunity.果蝇免疫。
Trends Cell Biol. 1997 Aug;7(8):309-16. doi: 10.1016/S0962-8924(97)01087-8.
2
Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms.果蝇的宿主防御：感染各类微生物后抗菌肽基因的差异诱导。
Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14614-9. doi: 10.1073/pnas.94.26.14614.
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Innate immunity: the virtues of a nonclonal system of recognition.固有免疫：非克隆识别系统的优势
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The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense.18轮大货车突变揭示了果蝇宿主防御中复杂的抗菌基因调控。
EMBO J. 1997 Oct 15;16(20):6120-30. doi: 10.1093/emboj/16.20.6120.
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A human homologue of the Drosophila Toll protein signals activation of adaptive immunity.果蝇Toll蛋白的人类同源物可发出适应性免疫激活的信号。
Nature. 1997 Jul 24;388(6640):394-7. doi: 10.1038/41131.
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Innate immunity: impact on the adaptive immune response.固有免疫：对适应性免疫应答的影响
Curr Opin Immunol. 1997 Feb;9(1):4-9. doi: 10.1016/s0952-7915(97)80152-5.
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A conserved signaling pathway: the Drosophila toll-dorsal pathway.一条保守的信号通路：果蝇Toll-Dorsal信号通路。
Annu Rev Cell Dev Biol. 1996;12:393-416. doi: 10.1146/annurev.cellbio.12.1.393.
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The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults.背腹侧调节基因盒spätzle/Toll/仙人掌控制果蝇成虫强大的抗真菌反应。
Cell. 1996 Sep 20;86(6):973-83. doi: 10.1016/s0092-8674(00)80172-5.
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The instructive role of innate immunity in the acquired immune response.固有免疫在获得性免疫应答中的指导作用。
Science. 1996 Apr 5;272(5258):50-3. doi: 10.1126/science.272.5258.50.
10
A conserved signal transduction pathway regulating the activity of the rel-like proteins dorsal and NF-kappa B.一条保守的信号转导途径，调节类rel蛋白背侧蛋白和核因子κB的活性。
Mol Biol Cell. 1993 Aug;4(8):767-71. doi: 10.1091/mbc.4.8.767.