• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

[Inhibitory effects of garlicin and cinnamaldehyde on SOS response and their mechanisms in Escherichia coli].

作者信息

Jin Z C

机构信息

Department of Pathophysiology, Zhejiang Medical University, Hangzhou.

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 1993 May;27(3):135-8.

PMID:8243172
Abstract

Inhibitory effects of garlicin and cinnamaldehyde on SOS response and their mechanisms in Escherichia coli were investigated. Garlicin and cinnamaldehyde suppressed the lambda cI depended SOS response induced by 4-nitroquinoline-N-oxide (4NQO), mytomycin (MMC) and methyl methane-sulfonate (MMS), and the lexA-depended SOS response induced by 4NQO and UV to various extent, respectively. They also diminished the rexA 441-depended SOS response induced by temperature (at 42 degrees C) However, they did not show any effect on the constitution of SOS functions. It suggested that this inhibitory effect could be via RecA protease which regulates the cleavage of lexA repressor, and perhaps, lambda cI repressor.

摘要

相似文献

1
[Inhibitory effects of garlicin and cinnamaldehyde on SOS response and their mechanisms in Escherichia coli].
Zhonghua Yu Fang Yi Xue Za Zhi. 1993 May;27(3):135-8.
2
Study of SOS-inducing kinetics and inhibitory effect on induction of Escherichia coli.SOS诱导动力学及对大肠杆菌诱导抑制作用的研究。
Chin Med J (Engl). 1990 Dec;103(12):1003-7.
3
Inhibition of spontaneous mutagenesis by vanillin and cinnamaldehyde in Escherichia coli: Dependence on recombinational repair.香兰素和肉桂醛对大肠杆菌自发诱变的抑制作用：依赖于重组修复
Mutat Res. 2006 Dec 1;602(1-2):54-64. doi: 10.1016/j.mrfmmm.2006.08.006. Epub 2006 Sep 26.
4
[Inhibitory effects of fifteen kinds of Chinese herbal drugs, vegetables and chemicals on SOS response].[十五种中草药、蔬菜及化学物质对SOS反应的抑制作用]
Zhonghua Yu Fang Yi Xue Za Zhi. 1994 May;28(3):147-50.
5
Analysis of the antimutagenic effect of cinnamaldehyde on chemically induced mutagenesis in Escherichia coli.肉桂醛对大肠杆菌化学诱导诱变的抗诱变作用分析。
Mol Gen Genet. 1983;192(3):309-15. doi: 10.1007/BF00392167.
6
Antimutagenic effects of cinnamaldehyde on chemical mutagenesis in Escherichia coli.肉桂醛对大肠杆菌化学诱变的抗诱变作用。
Mutat Res. 1983 Feb;107(2):219-27. doi: 10.1016/0027-5107(83)90164-1.
7
[Detection of SOS response inhibitor with E. coli GW1104 and GW1107 and its mechanism].
Zhonghua Yu Fang Yi Xue Za Zhi. 1994 Mar;28(2):84-7.
8
Inhibition of the transcriptional repressor LexA: Withstanding drug resistance by inhibiting the bacterial mechanisms of adaptation to antimicrobials.抑制转录抑制因子 LexA：通过抑制细菌对抗微生物药物适应机制来抵抗耐药性。
Life Sci. 2020 Jan 15;241:117116. doi: 10.1016/j.lfs.2019.117116. Epub 2019 Nov 29.
9
Interaction of Escherichia coli RecA protein with LexA repressor. II. Inhibition of DNA strand exchange by the uncleavable LexA S119A repressor argues that recombination and SOS induction are competitive processes.大肠杆菌RecA蛋白与LexA阻遏物的相互作用。II. 不可裂解的LexA S119A阻遏物对DNA链交换的抑制表明重组和SOS诱导是竞争性过程。
J Biol Chem. 1996 Sep 27;271(39):23874-83.
10
Temperature-dependent antimutagenic activity of acrolein in Escherichia coli.丙烯醛在大肠杆菌中与温度相关的抗诱变活性
Mutat Res. 1993 Feb;301(2):93-7. doi: 10.1016/0165-7992(93)90030-y.