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Preferential cytotoxicity of 5-thio-D-glucose against hypoxic tumor cells.

作者信息

Song C W, Clement J J, Levitt S H

出版信息

J Natl Cancer Inst. 1976 Sep;57(3):603-5. doi: 10.1093/jnci/57.3.603.

DOI:10.1093/jnci/57.3.603
PMID:824455
Abstract

5-Thio-D-glucose effectively killed hypoxic mastocytoma cells of DBA/2J mice, whereas it merely suppressed the growth of oxic cells. This specific toxicity suggested that 5-thio-D-glucose may be a useful adjuvant to radiotherapy by eliminating hypoxic protection.

摘要

相似文献

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Preferential cytotoxicity of 5-thio-D-glucose against hypoxic tumor cells.
J Natl Cancer Inst. 1976 Sep;57(3):603-5. doi: 10.1093/jnci/57.3.603.
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