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多动与拼写障碍:共享遗传病因的检测

Hyperactivity and spelling disability: testing for shared genetic aetiology.

作者信息

Stevenson J, Pennington B F, Gilger J W, DeFries J C, Gillis J J

机构信息

Behavioural Sciences Unit, University of London, U.K.

出版信息

J Child Psychol Psychiatry. 1993 Oct;34(7):1137-52. doi: 10.1111/j.1469-7610.1993.tb01779.x.

Abstract

The influence of genetic factors in the comorbidity of spelling disability and hyperactivity was investigated in two samples of 190 and 260 same sex twin pairs. The method of bivariate group heritability was used to estimate the genetic correlation for spelling disability and hyperactivity. A similar though not statistically significant value for the genetic correlation was obtained for the two samples (0.29 and 0.42). It was estimated that approximately 75% of the co-occurrence of these two conditions was due to shared genetic influences.

摘要

在两个分别由190对和260对同性双胞胎组成的样本中,研究了遗传因素在拼写障碍与多动共病中的影响。采用双变量组遗传率方法来估计拼写障碍和多动之间的遗传相关性。两个样本得到了相似但无统计学显著意义的遗传相关性值(0.29和0.42)。据估计,这两种情况同时出现的原因中,约75%是由于共同的遗传影响。

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