Alarcón M, DeFries J C, Light J G, Pennington B F
Department of Psychology, University of Colorado, Boulder, USA.
J Learn Disabil. 1997 Nov-Dec;30(6):617-23. doi: 10.1177/002221949703000605.
Although results obtained from recent twin and adoption studies suggest that individual differences in mathematics performance are due in part to heritable influences, no genetic analysis of mathematics disability (MD) has been previously reported. In this article we present data from the first twin sample ascertained for mathematics deficits (40 identical and 23 same-sex fraternal twin pairs in which at least one member had MD). When mathematics performance data from these twin pairs were subjected to a multiple regression analysis, evidence for a significant genetic etiology was obtained. However, tests for the differential etiology of MD as a function of reading performance level were nonsignificant. Results of this first twin study of MD indicate that the condition is significantly heritable, but data from additional twin pairs will be required to test hypotheses of differential etiology more rigorously.
尽管近期双胞胎和收养研究的结果表明，数学成绩的个体差异部分归因于遗传影响，但此前尚未有关于数学障碍（MD）的遗传分析报告。在本文中，我们展示了首个针对数学缺陷确定的双胞胎样本的数据（40对同卵双胞胎和23对同性异卵双胞胎，其中至少有一名成员患有MD）。当对这些双胞胎对的数学成绩数据进行多元回归分析时，获得了显著遗传病因的证据。然而，作为阅读成绩水平函数的MD差异病因测试并不显著。这项MD的首次双胞胎研究结果表明，该病症具有显著遗传性，但需要更多双胞胎对的数据来更严格地检验差异病因的假设。
