类风湿性关节炎患者血清和关节液的IgG亚类组成
IgG subclass composition of rheumatoid arthritic sera and joint fluids.
作者信息
Shakib F, Stanworth D R
出版信息
Ann Rheum Dis. 1976 Jun;35(3):263-6. doi: 10.1136/ard.35.3.263.
Abstract
The IgG subclass composition of 24 matched pairs of synovial fluids and sera, from 24 patients with rheumatoid arthritis, was determined. The subclass composition of rheumatoid synovial fluid IgG was found to be qualitatively the same as that of the corresponding serum, differing only in certain quantitative aspects. A 7-8% increase in IgG1 level found in the sera of rheumatoid arthritis patients relative to that in the sera of normal individuals was accompanied by 6-8, 0-7, and 0-3% decreases in IgG2, IgG3, and IgG4, respectively.
摘要
对24例类风湿性关节炎患者的24对匹配的滑液和血清的IgG亚类组成进行了测定。发现类风湿性滑液IgG的亚类组成在质量上与相应血清相同，仅在某些数量方面有所不同。类风湿性关节炎患者血清中IgG1水平相对于正常个体血清升高7 - 8%，同时IgG2、IgG3和IgG4分别下降6 - 8%、0 - 7%和0 - 3%。
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