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杆状病毒作为表达载体的应用。

The use of baculoviruses as expression vectors.

作者信息

Kidd I M, Emery V C

机构信息

Division of Communicable Diseases, Royal Free Hospital School of Medicine, Hampstead, London.

出版信息

Appl Biochem Biotechnol. 1993 Aug-Sep;42(2-3):137-59. doi: 10.1007/BF02788049.

DOI:10.1007/BF02788049
PMID:8250545
Abstract

The use of recombinant baculoviruses as high level expression systems is becoming more and more popular. This review aims to provide a summary of the impact of this expression system in biochemistry and biotechnology, highlighting important advances that have been made utilizing the system. The potential of newly developed multiple baculovirus expression systems to enable the reconstruction of complex biological molecules and processes is also reviewed.

摘要

重组杆状病毒作为高水平表达系统的应用正变得越来越普遍。本综述旨在总结该表达系统在生物化学和生物技术领域的影响，重点介绍利用该系统所取得的重要进展。同时也对新开发的多种杆状病毒表达系统在重建复杂生物分子和过程方面的潜力进行了综述。

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J Virol. 1993 Jan;67(1):229-38. doi: 10.1128/JVI.67.1.229-238.1993.
2
Production of human beta interferon in insect cells infected with a baculovirus expression vector.在感染杆状病毒表达载体的昆虫细胞中生产人β干扰素。
Mol Cell Biol. 1983 Dec;3(12):2156-65. doi: 10.1128/mcb.3.12.2156-2165.1983.
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Baculovirus expression vectors: the requirements for high level expression of proteins, including glycoproteins.
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Arch Virol. 2024 Aug 3;169(8):172. doi: 10.1007/s00705-024-06079-3.
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A construction strategy for a baculovirus-silkworm multigene expression system and its application for coexpression of type I and type II interferons.杆状病毒-家蚕多基因表达系统的构建策略及其在 I 型和 II 型干扰素共表达中的应用。
Microbiologyopen. 2020 Mar;9(3):e979. doi: 10.1002/mbo3.979. Epub 2019 Dec 19.
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