支气管扩张症与类风湿关节炎：一项临床研究。
Bronchiectasis and rheumatoid arthritis: a clinical study.
作者信息
McMahon M J, Swinson D R, Shettar S, Wolstenholme R, Chattopadhyay C, Smith P, Johns P, Crosby N H
机构信息
Wrightington Hospital, Wigan, United Kingdom.
出版信息
Ann Rheum Dis. 1993 Nov;52(11):776-9. doi: 10.1136/ard.52.11.776.
Abstract
OBJECTIVES
To examine the relation between rheumatoid arthritis (RA) and bronchiectasis (BR).
METHODS
Disease activity, outcome, extra-articular manifestations, and laboratory features were compared in 32 patients with BR and RA (RA-BR group), 32 matched patients with RA without BR (RA group), and 31 patients with BR but without arthritis (BR group).
RESULTS
In 30 of the 32 (94%) patients with RA-BR, BR preceded RA. There was no functional or radiological difference between the RA-BR and RA groups, and except for xerophthalmia, which was more common in patients with RA-BR than patients with RA, there was no difference in extra-articular or laboratory features.
CONCLUSIONS
Bronchiectasis does not lead to a more aggressive disease course in RA and, despite the recognised association, BR is not an extra-articular manifestation of rheumatoid disease.
摘要
目的
研究类风湿关节炎（RA）与支气管扩张（BR）之间的关系。
方法
比较32例患有BR和RA的患者（RA-BR组）、32例匹配的无BR的RA患者（RA组）和31例有BR但无关节炎的患者（BR组）的疾病活动度、预后、关节外表现和实验室特征。
结果
在32例RA-BR患者中的30例（94%）中，BR先于RA出现。RA-BR组和RA组之间在功能或影像学上没有差异，除了干眼症在RA-BR患者中比RA患者更常见外，关节外或实验室特征没有差异。
结论
支气管扩张不会导致RA出现更具侵袭性的病程，尽管存在公认的关联，但BR并非类风湿疾病的关节外表现。
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