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黑腹果蝇减数分裂重组和体细胞DNA代谢的遗传控制

Genetic controls of meiotic recombination and somatic DNA metabolism in Drosophila melanogaster.

作者信息

Baker B S, Boyd J B, Carpenter A T, Green M M, Nguyen T D, Ripoll P, Smith P D

出版信息

Proc Natl Acad Sci U S A. 1976 Nov;73(11):4140-4. doi: 10.1073/pnas.73.11.4140.

DOI:10.1073/pnas.73.11.4140
PMID:825857
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC431359/
Abstract

Recombination-defective meiotic mutants and mutagen-sensitive mutants of D. melanogaster have been examined for their effects on meiotic chromosome behavior, sensitivity to killing by mutagens, somatic chromosome integrity, and DNA repair processes. Several loci have been identified that specify functions that are necessary for both meiotic recombination and DNA repair processes, whereas mutants at combination and DNA repair processes, whereas mutants at other loci appear to be defective in only one pathway of DNA processing.

摘要

已经对黑腹果蝇的重组缺陷型减数分裂突变体和诱变剂敏感突变体进行了研究,以考察它们对减数分裂染色体行为、对诱变剂杀伤的敏感性、体细胞染色体完整性以及DNA修复过程的影响。已经鉴定出几个位点,这些位点所指定的功能对于减数分裂重组和DNA修复过程都是必需的,而其他位点的突变体似乎仅在DNA处理的一条途径中存在缺陷,而在减数分裂重组和DNA修复过程中存在缺陷。

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2
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本文引用的文献

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Somatic Crossing over and Segregation in Drosophila Melanogaster.果蝇中的体细胞交换与分离
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The Minute Reaction in the Development of DROSOPHILA MELANOGASTER.果蝇发育过程中的分钟反应。
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A THEORY OF CROSSING-OVER BY MEANS OF HYBRID DEOXYRIBONUCLEIC ACID.一种借助杂交脱氧核糖核酸实现交换的理论。
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Studies on a recombination-deficient mutant of Drosophila. I. Dominant lethals.果蝇重组缺陷型突变体的研究。I. 显性致死
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Genetics. 1968 Nov;60(3):525-58. doi: 10.1093/genetics/60.3.525.
6
[X-ray induced mitotic recombination in Drosophila melanogaster. II. The existence of two spectrum dependent reactions is proven, and both these reactions are characterized in more detail].[X射线诱导黑腹果蝇有丝分裂重组。II. 证明了存在两种光谱依赖性反应,并对这两种反应进行了更详细的表征]
Mol Gen Genet. 1971;113(2):132-49.
7
[X-ray induced mitotic recombination in Drosophila melanogaster. I. Its dependence on dose, dose-rate and spectrum].[X射线诱导黑腹果蝇有丝分裂重组。I. 其对剂量、剂量率和光谱的依赖性]
Mol Gen Genet. 1971;113(2):114-31.
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Discontinuities in the DNA synthesized in an excision-defective strain of Escherichia coli following ultraviolet irradiation.紫外线照射后,大肠杆菌切除缺陷菌株中合成的DNA的不连续性。
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Repair of UV-induced pyrimidine dimers in Drosophila melanogaster cells in vitro.体外修复果蝇细胞中紫外线诱导的嘧啶二聚体
Genetics. 1973 Feb;73(2):297-302. doi: 10.1093/genetics/73.2.297.
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Genetic analysis of sex chromosomal meiotic mutants in Drosophilia melanogaster.黑腹果蝇性染色体减数分裂突变体的遗传分析。
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