Li B, Gorziglia M
Epidemiology Section, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892.
J Clin Microbiol. 1993 Nov;31(11):3075-7. doi: 10.1128/jcm.31.11.3075-3077.1993.
The antigenic relationships of the VP4 serotype of porcine rotavirus Gottfried strain with other rotaviruses were determined by using antiserum to Gottfried VP4-baculovirus recombinant. This antiserum failed to react significantly with virus of serotypes P1A, P1B, P3, and OSU; however, it reacted with P2 strains. In the reciprocal assay, antiserum to VP4 of an asymptomatic strain (P2) failed to neutralize the Gottfried strain virus to a significant level. It thus appears that the Gottfried strain should be considered a subtype of P2.
通过使用抗戈特弗里德VP4-杆状病毒重组体的抗血清，确定了猪轮状病毒戈特弗里德株VP4血清型与其他轮状病毒之间的抗原关系。该抗血清与P1A、P1B、P3和俄亥俄州立大学血清型病毒无明显反应；然而，它与P2株有反应。在反向试验中来自无症状株（P2）的VP4抗血清未能显著中和戈特弗里德株病毒。因此，戈特弗里德株似乎应被视为P2的一个亚型。
