Su W, Jones P J
Division of Human Nutrition, University of British Columbia, Vancouver, Canada.
J Nutr. 1993 Dec;123(12):2109-14. doi: 10.1093/jn/123.12.2109.
To study the influence of dietary fatty acid composition on energy metabolism, forty male rats were fed elemental diets containing 42% of energy as fish oil, safflower oil, olive oil or beef tallow for 12 wk. Food intakes and body weights were measured daily. Energy expenditure and body composition were determined using doubly labeled water on the final 2 d. Pooled fecal energy losses differed in response to dietary manipulation, with losses greatest in rats fed beef tallow and least in those fed olive oil. Higher lean body mass gains and lower fat mass gains were observed in rats fed diets containing fish oil, compared with rats fed olive oil or beef tallow. Total energy gains in rats fed olive oil (3632 +/- 145 kJ) and beef tallow (3850 +/- 136 kJ) were higher than those in rats fed fish oil (2905 +/- 196 kJ). Energy efficiency in both the olive oil and beef tallow groups was also higher than that in the fish oil group. There were no differences in energy expenditure measured by doubly labeled water technique among the four groups. The data suggest that dietary fatty acid composition alters the efficiency of energy substrate accretion in rats.
为研究膳食脂肪酸组成对能量代谢的影响，将40只雄性大鼠喂以分别含有42%能量的鱼油、红花油、橄榄油或牛油的要素膳，持续12周。每天测量食物摄入量和体重。在最后2天使用双标水法测定能量消耗和身体组成。合并粪便能量损失对膳食处理的反应不同，喂牛油的大鼠损失最大，喂橄榄油的大鼠损失最小。与喂橄榄油或牛油的大鼠相比，喂含鱼油膳食的大鼠瘦体重增加更高，脂肪量增加更低。喂橄榄油（3632±145 kJ）和牛油（3850±136 kJ）的大鼠总能量增加高于喂鱼油的大鼠（2905±196 kJ）。橄榄油组和牛油组的能量效率也高于鱼油组。四组间用双标水技术测得的能量消耗没有差异。数据表明，膳食脂肪酸组成改变大鼠能量底物蓄积的效率。
