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关于4-甲基咪唑并非氨化草料中毒致病因素的进一步论证：幼龄羔羊的实验性种子干草中毒

Further arguments against 4-methylimidazole as causal factor in ammoniated forage toxicosis: experimental seed-hay poisoning in young lambs.

作者信息

Sivertsen T, Langseth W, Mo E, Ingebrigtsen K

机构信息

Department of Toxicology and Chemistry, National Veterinary Institute, Oslo, Norway.

出版信息

Acta Vet Scand. 1993;34(2):227-30. doi: 10.1186/BF03548216.

DOI:10.1186/BF03548216
PMID:8266904
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8112505/
Abstract

4-methylimidazole (4-MeI) is up to now the main tremorogenic poison known to be present in ammoniated roughages. The concentration of 4-MeI is widely used as an indicator of the potential toxicity of individual batches of ammoniated straw and hay.

摘要

4-甲基咪唑（4-MeI）是目前已知存在于氨化粗饲料中的主要致震颤毒素。4-甲基咪唑的浓度被广泛用作各批次氨化秸秆和干草潜在毒性的指标。

相似文献

1
Further arguments against 4-methylimidazole as causal factor in ammoniated forage toxicosis: experimental seed-hay poisoning in young lambs.关于4-甲基咪唑并非氨化草料中毒致病因素的进一步论证：幼龄羔羊的实验性种子干草中毒
Acta Vet Scand. 1993;34(2):227-30. doi: 10.1186/BF03548216.
2
Ammoniated forage poisoning: concentrations of alkylimidazoles in ammoniated forage and in milk, plasma and urine in sheep and cow.氨化饲料中毒：绵羊和奶牛的氨化饲料以及牛奶、血浆和尿液中烷基咪唑的浓度
Acta Vet Scand. 1998;39(4):511-4. doi: 10.1186/BF03547777.
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Ammoniated forage toxicosis in calves.犊牛氨化饲料中毒
J Am Vet Med Assoc. 1987 Sep 1;191(5):551-2.
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Etiology of ammoniated hay toxicosis.氨化干草中毒的病因
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引用本文的文献

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Cytotoxic effects of 4-methylimidazole on bone marrow mesenchymal stem cells in vitro.4-甲基咪唑对体外骨髓间充质干细胞的细胞毒性作用。
Am J Transl Res. 2015 Oct 15;7(10):1736-46. eCollection 2015.
2
Effects of 4-methylimidazole on cerebral glutamate decarboxylase activity and specific GABA receptor binding in mice.4-甲基咪唑对小鼠脑谷氨酸脱羧酶活性和特异性 GABA 受体结合的影响。
Toxicol Mech Methods. 2009 Mar;19(3):214-8. doi: 10.1080/15376510802488173.
3
Ammoniated forage poisoning: concentrations of alkylimidazoles in ammoniated forage and in milk, plasma and urine in sheep and cow.氨化饲料中毒：绵羊和奶牛的氨化饲料以及牛奶、血浆和尿液中烷基咪唑的浓度
Acta Vet Scand. 1998;39(4):511-4. doi: 10.1186/BF03547777.

本文引用的文献

1
Disposition of 4-methylimidazole in goats and heifers.4-甲基咪唑在山羊和小母牛体内的处置情况。
Res Vet Sci. 1993 Jan;54(1):72-9. doi: 10.1016/0034-5288(93)90014-7.
2
Etiology of ammoniated hay toxicosis.氨化干草中毒的病因
J Anim Sci. 1986 Aug;63(2):525-32. doi: 10.2527/jas1986.632525x.
3
Effects of 4-methylimidazole in young calves.4-甲基咪唑对犊牛的影响。
Vet Hum Toxicol. 1987 Aug;29(4):312-5.
4
Bovine bonkers: new terminology for an old problem a review of toxicity problems associated with ammoniated feeds.牛的疯狂：老问题的新术语——对与氨化饲料相关的毒性问题的综述
Vet Hum Toxicol. 1986 Feb;28(1):16-8.
5
Pharmacokinetics of 4-methylimidazole in sheep.4-甲基咪唑在绵羊体内的药代动力学
J Anim Sci. 1990 Oct;68(10):3277-84. doi: 10.2527/1990.68103277x.