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[Biochemical characterization of a circulating thymic factor].

作者信息

Bach J F, Dardenne M, Pleau J M, Rosa J

出版信息

C R Acad Hebd Seances Acad Sci D. 1976 Nov 29;283(14):1605-7.

PMID:827370
Abstract

A serum thymic factor has been isolated from pig serum. Its amino-acid sequence has been determined by Edman technique, modified by Gray: Gln-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn. A nonapeptide, synthesized on the basis of this sequence is active in the rosette assay used for the isolation of the biological product, both in vitro (10(-15) M) and in vivo (0.1 ng per Mouse).

摘要

相似文献

1
[Biochemical characterization of a circulating thymic factor].
C R Acad Hebd Seances Acad Sci D. 1976 Nov 29;283(14):1605-7.
2
Structural study of circulating thymic factor: a peptide isolated from pig serum. II. Amino acid sequence.
J Biol Chem. 1977 Nov 25;252(22):8045-7.
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Synthesis of a proposed thymic factor.
J Med Chem. 1979 May;22(5):586-8. doi: 10.1021/jm00191a026.
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Isolation from human plasma of a protein fraction with thymic hormone-like activity.从人血浆中分离出具有胸腺激素样活性的蛋白质组分。
Ann N Y Acad Sci. 1979;332:1-8. doi: 10.1111/j.1749-6632.1979.tb47092.x.
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Structural study of circulating thymic factor: a peptide isolated from pig serum. I. Isolation and purification.循环胸腺因子的结构研究:一种从猪血清中分离出的肽。I. 分离与纯化。
J Biol Chem. 1977 Nov 25;252(22):8040-4.
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A pioneer synthesis of conjugates of a thymic peptide hormone and polyamines.胸腺肽激素与多胺共轭物的开创性合成。
Biochem Biophys Res Commun. 1984 Jul 18;122(1):21-7. doi: 10.1016/0006-291x(84)90433-9.
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Biological activity of synthetic analogs of serum thymic factor.
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Thymosins and other hormones of the thymus gland.
Prog Clin Biol Res. 1981;58:191-215.
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Neonatal thymus grafts. I. Studies on the regulation of the level of circulating thymic factor (FTS).新生儿胸腺移植。I. 关于循环胸腺因子(FTS)水平调节的研究。
Immunology. 1979 Feb;36(2):207-13.
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Effects of antithymic reticuloepithelial cells serum on the levels of circulating thymic factor and on the sensitivity to azathioprine of spleen spontaneous rosette-forming cells.
Experientia. 1976 Nov 15;32(11):1475-6. doi: 10.1007/BF01937444.

引用本文的文献

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Extrathymic production of thymulin induced by oxidative stress, heat shock, apoptosis, or necrosis.由氧化应激、热休克、凋亡或坏死诱导的胸腺素的胸腺外产生。
Int J Immunopathol Pharmacol. 2017 Mar;30(1):58-69. doi: 10.1177/0394632017694625. Epub 2017 Feb 1.
2
Identification of thymostimulin secreting cells in calf thymus by immunoperoxidase method.通过免疫过氧化物酶法鉴定小牛胸腺中分泌胸腺刺激素的细胞。
Histochemistry. 1984;80(3):207-11. doi: 10.1007/BF00495767.