• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Structural study of circulating thymic factor: a peptide isolated from pig serum. II. Amino acid sequence.

作者信息

Pleau J M, Dardenne M, Blouquit Y, Bach J F

出版信息

J Biol Chem. 1977 Nov 25;252(22):8045-7.

PMID:914862
Abstract

The amino acid sequence of a circulating thymic factor (FTS, facteur thymique sérique) isolated from pig serum has been established as less than Glu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn-OH. This sequence was obtained by Edman analysis both on the intact peptide and after tryptic digestion. The COOH-terminal residue was identified by carboxypeptidase A digestion. A synthetic peptide was prepared which showed the same biological activities as native pig circulating thymic factor, thus confirming the proposed primary structure.

摘要

相似文献

1
Structural study of circulating thymic factor: a peptide isolated from pig serum. II. Amino acid sequence.
J Biol Chem. 1977 Nov 25;252(22):8045-7.
2
[Biochemical characterization of a circulating thymic factor].
C R Acad Hebd Seances Acad Sci D. 1976 Nov 29;283(14):1605-7.
3
Structural study of circulating thymic factor: a peptide isolated from pig serum. I. Isolation and purification.循环胸腺因子的结构研究：一种从猪血清中分离出的肽。I. 分离与纯化。
J Biol Chem. 1977 Nov 25;252(22):8040-4.
4
Radioimmunoassays for the thymic hormone serum thymic factor (FTS).胸腺激素血清胸腺因子（FTS）的放射免疫测定法。
J Immunol Methods. 1983 Feb 25;57(1-3):171-84. doi: 10.1016/0022-1759(83)90076-5.
5
Synthesis of analogs of the serum thymic nonapeptide, "facteur thymique serique" (FTS). Part I.
Int J Pept Protein Res. 1979 Jul;14(1):41-56. doi: 10.1111/j.1399-3011.1979.tb01919.x.
6
Synthesis of a proposed thymic factor.
J Med Chem. 1979 May;22(5):586-8. doi: 10.1021/jm00191a026.
7
Biological activity of synthetic analogs of serum thymic factor.
Int J Pept Protein Res. 1983 Feb;21(2):135-44. doi: 10.1111/j.1399-3011.1983.tb03087.x.
8
Synthesis of analogs of the serum thymic nonapeptide, "facteur thymique serique" (FTS). Part II.
Int J Pept Protein Res. 1980 Oct;16(4):267-79. doi: 10.1111/j.1399-3011.1980.tb02587.x.
9
The complete covalent structure of protein B. The third major protein degraded during germination of Bacillus megaterium spores.蛋白质B的完整共价结构。在巨大芽孢杆菌孢子萌发过程中降解的第三种主要蛋白质。
J Biol Chem. 1980 Nov 10;255(21):10445-50.
10
Neuroendocrine regulation of thymus hormones: hypothalamic dependence of "facteur thymique serique" level.胸腺激素的神经内分泌调节：“血清胸腺因子”水平对下丘脑的依赖性。
Cell Immunol. 1986 Oct 1;102(1):211-6. doi: 10.1016/0008-8749(86)90339-4.

引用本文的文献

1
Phosphorylation of synthetic acidic peptides by casein kinase II: evidence for competition with phosphorylation of proteins involved in transcription.
Mol Cell Biochem. 1993 Aug 11;125(1):65-72. doi: 10.1007/BF00926836.
2
In vitro induction of monoclonal antibody-defined T-cell markers in lymphocytes from immunodeficient children by synthetic serum thymic factor (FTS).合成血清胸腺因子（FTS）对免疫缺陷儿童淋巴细胞中单克隆抗体定义的T细胞标志物的体外诱导作用。
Clin Exp Immunol. 1982 May;48(2):423-8.
3
Characterization of facteur thymique sérique (FTS) in the thymus. I. Fixation of anti-FTS antibodies on thymic reticulo-epithelial cells.胸腺中血清胸腺因子（FTS）的特性研究。I. 抗FTS抗体在胸腺网状上皮细胞上的固定。
Clin Exp Immunol. 1980 Dec;42(3):470-6.
4
Induction of differentiation in human marrow T cell precursors by the synthetic serum thymic factor, FTS.合成血清胸腺因子FTS诱导人骨髓T细胞前体分化
Clin Exp Immunol. 1980 May;40(2):396-406.
5
Thymic hormone containing cells. III. Evidence for a feed-back regulation of the secretion of the serum thymic factor (FTS) by thymic epithelial cells.含胸腺激素细胞。III. 胸腺上皮细胞对血清胸腺因子（FTS）分泌进行反馈调节的证据。
Clin Exp Immunol. 1983 Apr;52(1):7-12.
6
Relationship between a spleen-derived immunosuppressive peptide 'SDIP' and the 'Facteur thymique sérique' (FTS): biochemical and biological comparison of the two factors.脾脏来源的免疫抑制肽“SDIP”与“血清胸腺因子”（FTS）之间的关系：两种因子的生化及生物学比较
Immunology. 1983 Apr;48(4):635-45.
7
Thymic hormone containing cells. II. Evolution of cells containing the serum thymic factor (FTS or thymulin) in normal and autoimmune mice, as revealed by anti-FTS monoclonal antibodies. Relationship with Ia bearing cells.含胸腺激素的细胞。II. 抗血清胸腺因子（FTS或胸腺生成素）单克隆抗体揭示的正常和自身免疫小鼠中含血清胸腺因子细胞的演变。与Ia阳性细胞的关系。
Clin Exp Immunol. 1983 Apr;52(1):1-6.
8
Isolation and characterization of DNA-binding peptides from the serum: inhibition of transcription and comparison with the tissue peptides.
Mol Biol Rep. 1982 Nov 30;8(4):217-23. doi: 10.1007/BF00776583.
9
The serum thymic factor (FTS). Chemical and biological aspects.血清胸腺因子（FTS）。化学与生物学特性
Mol Cell Biochem. 1981 Dec 4;41:67-72. doi: 10.1007/BF00225298.
10
Specific receptors for the serum thymic factor (FTS) in lymphoblastoid cultured cell lines.淋巴母细胞样培养细胞系中血清胸腺因子（FTS）的特异性受体
Proc Natl Acad Sci U S A. 1980 May;77(5):2861-5. doi: 10.1073/pnas.77.5.2861.