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阿尔茨海默型痴呆症中记忆加速减退

Accelerated forgetting in Alzheimer-type dementia.

作者信息

Larrabee G J, Youngjohn J R, Sudilovsky A, Crook T H

出版信息

J Clin Exp Neuropsychol. 1993 Sep;15(5):701-12. doi: 10.1080/01688639308402590.

DOI:10.1080/01688639308402590
PMID:8276930
Abstract

Accelerated forgetting of name-face associations and grocery list items within the first hour postpresentation is demonstrated in 80 persons with Alzheimer's disease (AD) compared to 80 control subjects matched on age, education, and gender. Differences in forgetting which exceeded statistical regression effects remained, even when AD and control subjects were matched on rate of acquisition during the learning trials of name-face associations. Results are discussed in relation to the neuropathology of AD, organic amnestic disorders, and methodological factors concerning previous research on forgetting in persons with AD.

摘要

与80名年龄、教育程度和性别相匹配的对照受试者相比,80名阿尔茨海默病(AD)患者在呈现后第一小时内对名字-面孔关联和购物清单项目的遗忘速度加快。即使在名字-面孔关联学习试验期间,AD患者和对照受试者在习得率上相匹配,超过统计回归效应的遗忘差异仍然存在。结合AD的神经病理学、器质性遗忘症以及先前关于AD患者遗忘研究的方法学因素对结果进行了讨论。

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