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Activities of potential therapeutic and prophylactic antibiotics against blood culture isolates of viridans group streptococci from neutropenic patients receiving ciprofloxacin.针对接受环丙沙星治疗的中性粒细胞减少患者的草绿色链球菌血培养分离株,潜在治疗性和预防性抗生素的活性。
Antimicrob Agents Chemother. 1993 Nov;37(11):2493-5. doi: 10.1128/AAC.37.11.2493.
2
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Molecular relationships and antimicrobial susceptibilities of viridans group streptococci isolated from blood of neutropenic cancer patients.从癌症中性粒细胞减少患者血液中分离出的草绿色链球菌的分子关系及抗菌药敏性
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Susceptibilities of streptococcal strains associated with infective endocarditis to nine antibiotics.
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E test versus agar dilution for antimicrobial susceptibility testing of viridans group streptococci.用于草绿色链球菌抗菌药物敏感性试验的E试验与琼脂稀释法比较
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In vitro activities of eight macrolide antibiotics and RP-59500 (quinupristin-dalfopristin) against viridans group streptococci isolated from blood of neutropenic cancer patients.八种大环内酯类抗生素及RP-59500(奎奴普丁-达福普汀)对从中性粒细胞减少的癌症患者血液中分离出的草绿色链球菌的体外活性。
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Emergence of high rates of antimicrobial resistance among viridans group streptococci in the United States.美国草绿色链球菌中出现高比例的抗菌药物耐药性。
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本文引用的文献

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Septicaemia caused by viridans streptococci in neutropenic patients with leukaemia.白血病中性粒细胞减少患者由草绿色链球菌引起的败血症。
Lancet. 1983;2(8365-66):1452-4. doi: 10.1016/s0140-6736(83)90799-7.
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Resistance in oral streptococci after repeated three-dose erythromycin prophylaxis.重复三剂红霉素预防后口腔链球菌的耐药性。
J Antimicrob Chemother. 1985 Apr;15(4):471-9. doi: 10.1093/jac/15.4.471.
3
Prevention of bacteremia caused by alpha-hemolytic streptococci by roxithromycin (RU-28 965) in granulocytopenic patients receiving ciprofloxacin.在接受环丙沙星治疗的粒细胞减少患者中,罗红霉素(RU-28965)对预防α溶血性链球菌引起的菌血症的作用
Infection. 1989 Jul-Aug;17(4):240-4. doi: 10.1007/BF01639528.
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Antimicrobial susceptibilities of Streptococcus species that cause septicemia in neutropenic patients.中性粒细胞减少患者中引起败血症的链球菌属的抗菌药敏性。
Antimicrob Agents Chemother. 1989 Apr;33(4):580-2. doi: 10.1128/AAC.33.4.580.
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Adult respiratory distress syndrome in neutropenic leukemia patients.中性粒细胞减少性白血病患者的成人呼吸窘迫综合征
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Antimicrobial susceptibility of viridans group streptococci isolated from patients with acute leukemia receiving ofloxacin for antibacterial prophylaxis.从接受氧氟沙星抗菌预防的急性白血病患者中分离出的草绿色链球菌的抗菌药敏性。
Infection. 1989 Nov-Dec;17(6):396-7. doi: 10.1007/BF01645556.
7
Alpha-streptococcal septicemia in leukemic children treated with continuous or large dosage intermittent cytosine arabinoside.接受持续或大剂量间歇性阿糖胞苷治疗的白血病儿童中的甲型链球菌败血症。
Pediatr Infect Dis J. 1989 Nov;8(11):755-8. doi: 10.1097/00006454-198911000-00005.
8
Outbreak of coagulase negative staphylococcus highly resistant to ciprofloxacin in a leukaemia unit.某白血病病房出现对环丙沙星高度耐药的凝固酶阴性葡萄球菌暴发。
BMJ. 1989 Jul 29;299(6694):294-7. doi: 10.1136/bmj.299.6694.294.
9
Streptococcal bacteremia in adult patients with leukemia undergoing aggressive chemotherapy. A review of 55 cases.接受强化化疗的成年白血病患者的链球菌菌血症。55例病例回顾。
Infection. 1990 May-Jun;18(3):138-45. doi: 10.1007/BF01642101.
10
Respiratory failure elicited by streptococcal septicaemia in patients treated with cytosine arabinoside, and its prevention by penicillin.接受阿糖胞苷治疗的患者因链球菌败血症引发呼吸衰竭,以及青霉素对其的预防作用。
Infection. 1990 May-Jun;18(3):131-7. doi: 10.1007/BF01642100.

针对接受环丙沙星治疗的中性粒细胞减少患者的草绿色链球菌血培养分离株,潜在治疗性和预防性抗生素的活性。

Activities of potential therapeutic and prophylactic antibiotics against blood culture isolates of viridans group streptococci from neutropenic patients receiving ciprofloxacin.

作者信息

McWhinney P H, Patel S, Whiley R A, Hardie J M, Gillespie S H, Kibbler C C

机构信息

Department of Microbiology, Royal Free Hospital School of Medicine, London, United Kingdom.

出版信息

Antimicrob Agents Chemother. 1993 Nov;37(11):2493-5. doi: 10.1128/AAC.37.11.2493.

DOI:10.1128/AAC.37.11.2493
PMID:8285642
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC192417/
Abstract

All 47 sequential blood culture isolates of viridans group streptococci obtained from febrile neutropenic patients receiving quinolone prophylaxis were susceptible to vancomycin, teicoplanin, and imipenem. Resistance to benzylpenicillin (MIC for 50% of isolates [MIC50], 0.125 microgram/ml) and ceftazidime (MIC50, 4 micrograms/ml) was common. Most isolates were susceptible to amoxicillin, co-amoxiclav (amoxicillin-clavulanic acid at a 2:1 ratio by weight), azlocillin, clarithromycin, and erythromycin, with azithromycin showing comparable activity. The MIC90 of sparfloxacin was 1 microgram/ml; those for ciprofloxacin and ofloxacin were > 16 and 16 micrograms/ml, respectively.

摘要

从接受喹诺酮预防治疗的发热性中性粒细胞减少患者中获得的47株连续性草绿色链球菌血培养分离株,对万古霉素、替考拉宁和亚胺培南均敏感。对苄青霉素(50%分离株的MIC[MIC50],0.125微克/毫升)和头孢他啶(MIC50,4微克/毫升)耐药很常见。大多数分离株对阿莫西林、阿莫西林克拉维酸(按重量比2:1的阿莫西林-克拉维酸)、阿洛西林、克拉霉素和红霉素敏感,阿奇霉素显示出相当的活性。司帕沙星的MIC90为1微克/毫升;环丙沙星和氧氟沙星的MIC90分别>16和16微克/毫升。