中性粒细胞减少患者中引起败血症的链球菌属的抗菌药敏性。
Antimicrobial susceptibilities of Streptococcus species that cause septicemia in neutropenic patients.
作者信息
Venditti M, Baiocchi P, Santini C, Brandimarte C, Serra P, Gentile G, Girmenia C, Martino P
机构信息
Cattedra di Patologia Medica III, Università La Sapienza, Rome, Italy.
出版信息
Antimicrob Agents Chemother. 1989 Apr;33(4):580-2. doi: 10.1128/AAC.33.4.580.
Abstract
Sixty-three consecutive streptococcal blood isolates from neutropenic patients, represented mainly by viridans group streptococci, were evaluated in vitro for antibiotic susceptibility. Of these isolates, 79.3% were highly susceptible to penicillin (MIC, less than or equal to 0.12 microgram/ml). Overall, imipenem was the most active agent, followed by teicoplanin and vancomycin. All other agents showed decreased activity against streptococcal isolates that were not highly susceptible to penicillin.
摘要
对63株来自中性粒细胞减少患者的连续链球菌血培养分离株（主要为草绿色链球菌）进行了体外抗生素敏感性评估。在这些分离株中，79.3%对青霉素高度敏感（MIC≤0.12微克/毫升）。总体而言，亚胺培南是活性最强的药物，其次是替考拉宁和万古霉素。所有其他药物对非高度敏感青霉素的链球菌分离株活性均降低。
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