Wang K K, Costas P D, Bryan D J, Jones D S, Seckel B R
Department of Plastic and Reconstructive Surgery, Lahey Clinic Medical Center, Burlington, MA 01805.
Microsurgery. 1993;14(9):608-18. doi: 10.1002/micr.1920140914.
Vein grafts have been used both experimentally and clinically to bridge gaps in peripheral nerves. This study describes a modification of the vein graft technique in which vein graft conduits are pulled inside-out before anastomosis with proximal and distal nerve stumps. This technique creates an autogenous vein conduit with the collagen-rich adventitial surface exposed to the regenerating axons. The inside-out technique is a fast and simple modification of the standard vein graft technique and produces an accelerated rate of nerve regeneration and significantly earlier myelination compared with the results obtained from the use of polyethylene nerve guides and standard vein graft conduits.
静脉移植已在实验和临床中用于桥接周围神经的缺损。本研究描述了一种静脉移植技术的改良方法，即在与近端和远端神经残端吻合之前，将静脉移植导管由内向外翻转。该技术创建了一个自体静脉导管，其富含胶原蛋白的外膜表面暴露于再生轴突。由内向外技术是标准静脉移植技术的一种快速且简单的改良方法，与使用聚乙烯神经导管和标准静脉移植导管所获得的结果相比，它能加快神经再生速度并显著提前髓鞘形成。
