Benes J, Proksová M, Hrusovský J
Vet Med (Praha). 1976 Dec;21(12):737-46.
In a model of sheep perorally intoxicated with a 200.0 mg kg-1 trichlorphon dose, the effectivity of the worked out therapeutical procedure was confirmed; the procedure consisted in the administration of an anticholinergic (20.0 mg of 1.1% atropine s. c. pro toto) and cholinesterase reactivator (30.0 mg of 10% trimedoxime kg-1 i. m.) mixture 4 hours after the administration of the noxious agent. A determination of the erythrocytic acetylcholinesterase (AChE, E.C.3.1.1.7.) and plasmatic butyrylcholinesterase (BChE, E.C.3.1.1.8.) activities in the intoxicated sheep should be considered a decisive clinical and diagnostical test for taking veterinary-therapeutical, veterinary-hygienical or veterinary-sanitary measures in intoxications with anti-cholinesterase substances on the whole.
在绵羊经口摄入200.0毫克/千克敌百虫剂量而中毒的模型中，所制定治疗程序的有效性得到了证实；该程序包括在给予有毒物质4小时后，皮下注射抗胆碱能药物（20.0毫克1.1%阿托品，总量）和肌肉注射胆碱酯酶复活剂（30.0毫克10%双复磷/千克）的混合物。对于整个抗胆碱酯酶物质中毒情况，测定中毒绵羊的红细胞乙酰胆碱酯酶（AChE，E.C.3.1.1.7.）和血浆丁酰胆碱酯酶（BChE，E.C.3.1.1.8.）活性应被视为采取兽医治疗、兽医卫生或兽医卫生措施的决定性临床和诊断测试。
