Spyckerelle Y, Fournier B, Bon N, Deschamps J P
Centre de médecine préventive, Unité de recherche, Vandoeuvre-lès-Nancy.
Arch Mal Coeur Vaiss. 1993 Jul;86(7):1047-52.
In order to assess the relationship between changes in life style (taking up smoking, giving up sporting activity) and plasma lipids, 3,650 young subjects aged 14 to 18 years, from the Lorraine region, were examined on two occasions separated by a 5 year interval. At the second examination, 39% of the boys and 33.8% of the girls had taken up smoking, and 52% of the boys and 68% of the girls had given up strenuous physical activity. These changes in life style were associated with a significant change in total cholesterol in boys and also of triglycerides after adjustment of values for age and variation in body mass: starting smoking or the giving up of sporting activities was associated with a greater increase in cholesterol and triglyceride levels. These results underline need for increasing efforts in the prevention of cardiovascular disease in young subjects, and emphasise the importance of maintaining physical activity and of not smoking.
为了评估生活方式的改变（开始吸烟、放弃体育活动）与血脂之间的关系，对来自洛林地区的3650名14至18岁的年轻受试者进行了两次检查，两次检查间隔5年。在第二次检查时，39%的男孩和33.8%的女孩开始吸烟，52%的男孩和68%的女孩放弃了剧烈体育活动。在对年龄和体重变化值进行调整后，这些生活方式的改变与男孩总胆固醇以及甘油三酯的显著变化有关：开始吸烟或放弃体育活动与胆固醇和甘油三酯水平的更大升高有关。这些结果强调了在年轻受试者中加大心血管疾病预防力度的必要性，并强调了保持体育活动和不吸烟的重要性。
