用抗二聚体血清检测真核细胞中嘧啶二聚体切除修复的特征。
Characteristics of excision repair of pyrimidine dimers in eukaryotic cells as assayed with anti-dimer sera.
作者信息
Cornelis J J
出版信息
Nucleic Acids Res. 1978 Nov;5(11):4273-81. doi: 10.1093/nar/5.11.4273.
Abstract
An antiserum that recognizes the three types of pyrimidine dimers induced by UV-light in DNA was used to monitor their removal from eukaryotic cell nuclei. Cells able to excise dimers display a similar removal pattern: a fast process completed within a few hours leaving many dimers in the DNA.
摘要
一种能识别紫外线在DNA中诱导产生的三种嘧啶二聚体的抗血清，被用于监测其从真核细胞核中的去除情况。能够切除二聚体的细胞呈现出相似的去除模式：一个在几小时内完成的快速过程，使得DNA中仍留下许多二聚体。
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