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A novel quinone antibiotic from Malbranchea cinnamomea TAIM 13T54.

作者信息

Chiung Y M, Fujita T, Nakagawa M, Nozaki H, Chen G Y, Chen Z C, Nakayama M

机构信息

Department of Agricultural Chemistry, University of Osaka Prefecture, Japan.

出版信息

J Antibiot (Tokyo). 1993 Dec;46(12):1819-26. doi: 10.7164/antibiotics.46.1819.

DOI:10.7164/antibiotics.46.1819
PMID:8294239
Abstract

A novel quinone antibiotic named malbranicin was isolated from the culture filtrate and mycelium of Malbranchea cinnamomea TAIM 13T54, a thermophilic fungus. The antibiotic was elucidated to be 6-(1-acetylethyl)-2-methoxy-2,5-cyclohexadiene-1,4-dione by spectral analysis. Malbranicin exhibited antimicrobial and cytotoxic activities against Gram-positive bacteria and mammalian cell lines, respectively.

摘要

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