新型抗生素FR-900336的分类学、分离及特性研究

Studies on a new antibiotic FR-900336 taxonomy, isolation and characterization.

作者信息

Hino M, Kino E, Komori T, Kohsaka M

出版信息

J Antibiot (Tokyo). 1984 Apr;37(4):303-8. doi: 10.7164/antibiotics.37.303.

DOI:10.7164/antibiotics.37.303

Abstract

A new lipophilic antibiotic, FR-900336 was isolated from a culture of Streptomyces sioyaensis subsp. tanegashimaensis . FR-900336 is light yellow and has a molecular formula C30H30NO13C1 . The characterization by IR, UV, 1H NMR and 13C NMR spectra makes a quinone structure very probable. FR-900336 is active against Gram-positive bacteria and fungi.

摘要

一种新的亲脂性抗生素FR-900336是从岛链霉菌种子岛亚种的培养物中分离出来的。FR-900336为浅黄色，分子式为C30H30NO13C1。通过红外光谱、紫外光谱、1H核磁共振谱和13C核磁共振谱进行的表征极有可能显示其具有醌结构。FR-900336对革兰氏阳性菌和真菌具有活性。