O抗原在粘质沙雷氏菌对非免疫血清易感性中的作用。
The role of O-antigen in susceptibility of Serratia marcescens to non-immune serum.
作者信息
Palomar J, Montilla R, Fusté M C, Viñas M
机构信息
Department of Microbiology and Parasitology, Faculty of Pharmacy, University of Barcelona, Spain.
出版信息
Microbios. 1993;76(308):189-96.
Selection of phage-resistant strains to three different phages, kappa, FSB3 and FSB55, whose primary receptor was lipopolysaccharide, enabled several spontaneous O-defective mutants to be isolated and characterized. Strains ATCC 274 (0:14), 2170 (0:14) and NIMA (0:6) showed serum resistance, whereas their O-side chain defective mutants exhibited high serum susceptibility. Both alternate and classical activation pathways were involved in serum killing activity in Serratia marcescens.
选择对三种不同噬菌体（κ、FSB3和FSB55）具有抗性的菌株，这些噬菌体的主要受体是脂多糖，这使得能够分离和鉴定出几个自发的O-缺陷型突变体。菌株ATCC 274（O:14）、2170（O:14）和NIMA（O:6）表现出血清抗性，而它们的O侧链缺陷型突变体则表现出高血清敏感性。交替激活途径和经典激活途径都参与了粘质沙雷氏菌的血清杀伤活性。
Zotero 插件