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氯氮平治疗难治性精神病性抑郁症。

Clozapine in the treatment of psychotic refractory depression.

作者信息

Dassa D, Kaladjian A, Azorin J M, Giudicelli S

机构信息

Department of Psychiatry, Timone Hospital, Marseille, France.

出版信息

Br J Psychiatry. 1993 Dec;163:822-4. doi: 10.1192/bjp.163.6.822.

DOI:10.1192/bjp.163.6.822
PMID:8306130
Abstract

A 40-year-old woman suffering from major depression with psychotic features was unresponsive to conventional therapy. After the administration of a wide range of drug treatments and ECT, she received clozapine. Depressive symptoms improved and psychotic features disappeared. It is suggested that clozapine could be efficient in psychotic refractory depression.

摘要

一名患有伴有精神病性特征的重度抑郁症的40岁女性对传统治疗无反应。在接受了广泛的药物治疗和电休克治疗后，她开始服用氯氮平。抑郁症状有所改善，精神病性特征消失。提示氯氮平对难治性精神病性抑郁症可能有效。

相似文献

1
Clozapine in the treatment of psychotic refractory depression.氯氮平治疗难治性精神病性抑郁症。
Br J Psychiatry. 1993 Dec;163:822-4. doi: 10.1192/bjp.163.6.822.
2
Combined electroconvulsive-clozapine therapy.电休克合并氯氮平治疗
Clin Neuropharmacol. 2000 Jan-Feb;23(1):14-6. doi: 10.1097/00002826-200001000-00003.
3
Clozapine following ECT: a two-step treatment.
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4
Should the administration of ECT during clozapine therapy be contraindicated?在氯氮平治疗期间进行电休克治疗是否应被视为禁忌？
Br J Psychiatry. 1996 Aug;169(2):253-4. doi: 10.1192/bjp.169.2.253b.
5
Acute and long-term effectiveness of clozapine in treatment-resistant psychotic depression.氯氮平治疗难治性精神病性抑郁症的急性和长期疗效
Biol Psychiatry. 1996 Aug 15;40(4):253-8. doi: 10.1016/0006-3223(95)00305-3.
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[Risperidone after clozapine in therapy refractory schizoaffective psychosis--a case report].[难治性分裂情感性精神病中氯氮平之后使用利培酮——一例报告]
Psychiatr Prax. 1997 Mar;24(2):88-9.
7
Clozapine treatment of adolescents with posttraumatic stress disorder and psychotic symptoms.氯氮平治疗患有创伤后应激障碍和精神病性症状的青少年。
J Clin Psychopharmacol. 2004 Apr;24(2):167-73. doi: 10.1097/01.jcp.0000116650.91923.1d.
8
Supraventricular tachycardia in a patient receiving ECT, clozapine, and caffeine.一名接受电休克治疗、服用氯氮平和咖啡因的患者出现室上性心动过速。
Convuls Ther. 1994 Sep;10(3):228-31.
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Clozapine therapy in refractory affective disorders: polarity predicts response in long-term follow-up.氯氮平治疗难治性情感障碍：极性可预测长期随访中的反应。
J Clin Psychiatry. 1994 Jul;55(7):295-300.
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[The treatment of psychotic depression in patients insufficiently responsive to conventional medication and electroconvulsive therapy; what are the options?].[对传统药物治疗和电休克治疗反应欠佳的精神病性抑郁症患者的治疗；有哪些选择？]
Tijdschr Psychiatr. 2008;50(2):107-12.

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Clozapine: Current perspective.氯氮平：现状。
Indian J Psychiatry. 2007 Oct;49(4):271-6. doi: 10.4103/0019-5545.37668.
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A case study evaluating the use of clozapine in depression with psychotic features.一项评估氯氮平在伴有精神病性特征的抑郁症中应用的病例研究。
Ann Gen Psychiatry. 2006 Nov 29;5:20. doi: 10.1186/1744-859X-5-20.
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Psychotic major depression: a benefit-risk assessment of treatment options.精神病性重度抑郁症：治疗方案的获益-风险评估
Drug Saf. 2006;29(6):491-508. doi: 10.2165/00002018-200629060-00003.
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Antidepressive effects of traditional and second generation antipsychotics: a review of the clinical data.传统及第二代抗精神病药物的抗抑郁作用：临床数据综述
Eur Arch Psychiatry Clin Neurosci. 2005 Apr;255(2):83-93. doi: 10.1007/s00406-005-0580-z.
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Electroconvulsive therapy for the treatment of clozapine nonresponders suffering from schizophrenia--an open label study.电休克疗法治疗氯氮平无反应的精神分裂症患者——一项开放性研究。
Eur Arch Psychiatry Clin Neurosci. 2004 Dec;254(6):372-9. doi: 10.1007/s00406-004-0517-y. Epub 2004 Nov 12.
7
Synergistic dopamine increase in the rat prefrontal cortex with the combination of quetiapine and fluvoxamine.喹硫平与氟伏沙明联合使用可使大鼠前额叶皮质中的多巴胺协同增加。
Psychopharmacology (Berl). 2004 Nov;176(2):195-203. doi: 10.1007/s00213-004-1880-0. Epub 2004 May 11.
8
Evaluation of newer treatment interventions for psychotic depression.对精神病性抑郁新治疗干预措施的评估。
Curr Psychiatry Rep. 2000 Aug;2(4):305-9. doi: 10.1007/s11920-000-0072-9.