Suominen H, Heikkinen E, Parkatti T
J Gerontol. 1977 Jan;32(1):33-7. doi: 10.1093/geronj/32.1.33.
Five one-hour exercise periods a week for 8 weeks included walking-jogging, swimming, gymnastics and ballgames for 26 healthy male and female 69-year-old pensioners. The mean maximal oxygen uptake of the men increased from 28.9 ml-kg-1-min-1 before training to 32.0 ml-kg-1-min-1 after training and for the women from 27.9 to 31.3 ml-kg-1-min-1. Muscle malate dehydrogenase activity was increased while that for lactate dehydrogenase decreased or remained the same. The activity of these enzymes was higher in the male both before and after training when compared with the female. However, the percentage number of slow twitch muscle fibers was nearly the same in both groups. Prolyl hydroxylase activity was increased after training especially in the female subjects. These results show that endurance-type training leads to an enhanced capacity for aerobic metabolism in older subjects and that collagen metabolism in skeletal muscles is affected by physical training.
26名69岁的健康男性和女性退休人员，连续8周每周进行5次、每次1小时的锻炼，锻炼项目包括快走-慢跑、游泳、体操和球类运动。男性的平均最大摄氧量从训练前的28.9毫升·千克⁻¹·分钟⁻¹增加到训练后的32.0毫升·千克⁻¹·分钟⁻¹，女性则从27.9毫升·千克⁻¹·分钟⁻¹增加到31.3毫升·千克⁻¹·分钟⁻¹。肌肉苹果酸脱氢酶活性增加，而乳酸脱氢酶活性降低或保持不变。与女性相比，男性在训练前后这些酶的活性都更高。然而，两组中慢肌纤维的百分比几乎相同。训练后脯氨酰羟化酶活性增加，尤其是女性受试者。这些结果表明，耐力型训练可提高老年受试者的有氧代谢能力，且体育锻炼会影响骨骼肌中的胶原蛋白代谢。
