Suominen H, Heikkinen E
Eur J Appl Physiol Occup Physiol. 1975 Dec 5;34(4):249-54. doi: 10.1007/BF00999938.
A cross-sectional study was carried out to examine the activities of certain enzymes representing aerobic and anaerobic energy metabolism as well as the biosynthesis of collagen of M. vastus lateralis in 23 male endurance athletes in habitual training, aged 33 to 70 years. 23 sedentary healthy men of corresponding ages were selected for the control group. The mean maximal oxygen uptake of the trained subjects was 53.6 ml-kg--1. min--1 and that of the control subjects 36.3 ml-kg--1. min--1. As compared to the control group the trained subjects had significantly higher values in the muscle malate dehydrogenase, succinate dehydrogenase and prolyl hydroxylase activities, whereas the opposite was true in the activity of lactate dehydrogenase. In hexokinase and creatine phosphokinase no marked differences between the groups were observed. The results showed that endurance training leads to increased activities of oxidative enzymes in the skeletal muscle. The adaptation changes were also observed in old men. The increased activity of prolyl hydroxylase may reflect the general enzymatic adaptation to physical training. A possibility exists that the turnover of muscle collagen in endurance athelets is continuously faster than that in sedentary men of corresponding ages.
对23名年龄在33至70岁之间、长期进行训练的男性耐力运动员的股外侧肌进行了一项横断面研究，以检测代表有氧和无氧能量代谢的某些酶的活性以及胶原蛋白的生物合成。选择23名年龄相仿的久坐不动的健康男性作为对照组。训练组受试者的平均最大摄氧量为53.6 ml·kg⁻¹·min⁻¹，对照组受试者为36.3 ml·kg⁻¹·min⁻¹。与对照组相比，训练组受试者的肌肉苹果酸脱氢酶、琥珀酸脱氢酶和脯氨酰羟化酶活性显著更高，而乳酸脱氢酶活性则相反。在己糖激酶和肌酸磷酸激酶方面，两组之间未观察到明显差异。结果表明，耐力训练会导致骨骼肌中氧化酶活性增加。在老年男性中也观察到了适应性变化。脯氨酰羟化酶活性的增加可能反映了对体育锻炼的一般酶适应性。耐力运动员肌肉胶原蛋白的更新速度可能持续快于同龄久坐男性。
