炎症与愈合过程中的凝血酶：与类风湿关节炎的相关性 - Suppr

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超能文献

Thrombin in inflammation and healing: relevance to rheumatoid arthritis.

作者信息

Morris R, Winyard P G, Blake D R, Morris C J

机构信息

Inflammation Research Group, London Hospital Medical College, United Kingdom.

出版信息

Ann Rheum Dis. 1994 Jan;53(1):72-9. doi: 10.1136/ard.53.1.72.

DOI:10.1136/ard.53.1.72

PMID:8311562

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1005249/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95dc/1005249/6f3fd8a09624/annrheumd00489-0080-a.jpg

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本文引用的文献

THE EFFECT OF EXPERIMENTAL HEMARTHROSIS ON ARTICULAR CARTILAGE OF RABBIT KNEE JOINTS.实验性关节积血对兔膝关节软骨的影响

J Bone Joint Surg Am. 1965 Sep;47:1203-10.

The mitogenic effect of thrombin in vascular smooth muscle cells is largely due to basic fibroblast growth factor.凝血酶在血管平滑肌细胞中的促有丝分裂作用很大程度上归因于碱性成纤维细胞生长因子。

J Biol Chem. 1993 Mar 15;268(8):5724-7.

Specific glycosaminoglycans support the inhibition of thrombin by plasminogen activator inhibitor 1.特定的糖胺聚糖可支持纤溶酶原激活物抑制剂1对凝血酶的抑制作用。

Biochemistry. 1993 Feb 16;32(6):1675-80. doi: 10.1021/bi00057a035.

Regulation of protease nexin-1 synthesis and secretion in cultured brain cells by injury-related factors.

J Biol Chem. 1993 Feb 15;268(5):3720-7.

The N-terminal thrombin receptor fragment SFLLRN, but not catalytically inactive thrombin-derived agonists, activate U937 human monocytic cells: evidence for receptor hydrolysis in thrombin-dependent signalling.N 端凝血酶受体片段 SFLLRN 可激活 U937 人单核细胞，而催化失活的凝血酶衍生激动剂则不能：这是凝血酶依赖性信号传导中受体水解的证据。

Biochem J. 1993 Mar 1;290 ( Pt 2)(Pt 2):571-7. doi: 10.1042/bj2900571.

Glycosaminoglycans and the regulation of blood coagulation.糖胺聚糖与血液凝固的调节

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J Clin Invest. 1993 Jun;91(6):2609-19. doi: 10.1172/JCI116500.

Biologically active thrombomodulin is synthesized by adherent synovial fluid cells and is elevated in synovial fluid of patients with rheumatoid arthritis.生物活性血栓调节蛋白由黏附的滑液细胞合成，在类风湿关节炎患者的滑液中含量升高。

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