Reed T, Carmelli D, Christian J C, Selby J V, Fabsitz R R
Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis 46202.
Genet Epidemiol. 1993;10(6):513-7. doi: 10.1002/gepi.1370100630.
The National Heart, Lung and Blood Institute (NHLBI) twin study is a collaborative, longitudinal study of the role of genetic risk factors on subsequent cardiovascular disease processes in 514 pairs of white, male World War II and Korean veteran twins born between 1917 and 1927. This paper describes the sampling procedures and zygosity determination at the initial examination, participation by the cohort members at later examinations, and a summary of the variables provided for Genetic Analysis Workshop 8 (GAW8).
美国国立心肺血液研究所（NHLBI）双胞胎研究是一项针对514对白人男性双胞胎开展的合作性纵向研究，这些双胞胎均为二战及朝鲜战争老兵，出生于1917年至1927年之间，该研究旨在探究遗传风险因素对后续心血管疾病进程的作用。本文描述了初次检查时的抽样程序和同卵双生判定方法、队列成员在后续检查中的参与情况，以及为遗传分析研讨会8（GAW8）提供的变量汇总。
