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心肌灌注显像中人员辐射剂量测定的比较:锝-99m-甲氧基异丁基异腈与铊-201

Comparison of personnel radiation dosimetry from myocardial perfusion scintigraphy: technetium-99m-sestamibi versus thallium-201.

作者信息

Culver C M, Dworkin H J

机构信息

Nuclear Medicine Department, William Beaumont Hospital, Royal Oak, MI 48073-6769.

出版信息

J Nucl Med. 1993 Jul;34(7):1210-3.

PMID:8315504
Abstract

The whole-body and hand radiation doses to our technical staff were retrospectively compared for three distinct 4-mo periods when either 201TI or 99mTc-sestamibi were exclusively used for stress myocardial perfusion imaging. During the initial 4-mo period when 99mTc-sestamibi replaced 201TI, the mean whole-body film badge readings increased from 100 to 450 microSv/mo (p < 0.001) for nuclear medicine technologists (n = 10) and from 240 to 560 microSv/mo (p < 0.05) for radiopharmacy technologists (n = 2). Mean TLD readings to the hands also increased, although the differences were not statistically significant for the nuclear medicine technologists. Noninvasive cardiology staff were monitored with film badges and the mean whole-body film badge reading, when 99mTc-sestamibi was the imaging agent, was 360 microSv per month. Radiation reduction methods that decreased radiation exposure to staff were utilized. The most effective included the use of a lead face shield and lead lined storage container in the noninvasive imaging area, handling spills by shielding instead of decontamination and methods to reduce time spent in close proximity to the patient.

摘要

我们对技术人员的全身和手部辐射剂量进行了回顾性比较,比较了三个不同的4个月时间段,在这些时间段中,分别单独使用201铊或99锝-司他米比进行心肌灌注显像。在最初的4个月时间段,即99锝-司他米比取代201铊期间,核医学技术人员(n = 10)的平均全身胶片剂量计读数从每月100微希沃特增加到450微希沃特(p < 0.001),放射药学技术人员(n = 2)的读数从每月240微希沃特增加到560微希沃特(p < 0.05)。手部的平均热释光剂量计读数也有所增加,尽管核医学技术人员的差异无统计学意义。非侵入性心脏病学工作人员使用胶片剂量计进行监测,当使用99锝-司他米比作为显像剂时,平均全身胶片剂量计读数为每月360微希沃特。我们采用了减少工作人员辐射暴露的方法。最有效的方法包括在非侵入性成像区域使用铅面罩和铅衬储存容器,通过屏蔽而非去污来处理溢出物,以及减少与患者近距离接触时间的方法。

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Comparison of personnel radiation dosimetry from myocardial perfusion scintigraphy: technetium-99m-sestamibi versus thallium-201.心肌灌注显像中人员辐射剂量测定的比较:锝-99m-甲氧基异丁基异腈与铊-201
J Nucl Med. 1993 Jul;34(7):1210-3.
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