Taylor S A, Hooton N S, Macarthur A M
Br J Surg. 1977 Jan;64(1):52-3. doi: 10.1002/bjs.1800640113.
Twenty-five patients with malignant pleural effusion were treated with a single intrapleural dose of Quinacrine. Eighteen patients (72 per cent) had a significant response, with no reaccumulation of fluid for at least 2 months following treatment up to a maximum of 18 months in 2 patients. Seven patients (28 per cent) survived for longer than 1 year without evidence of recurrent effusion.
25例恶性胸腔积液患者接受了胸腔内单次注射阿的平治疗。18例患者（72%）有显著反应，治疗后至少2个月胸腔内无液体再积聚，2例患者最长达18个月。7例患者（28%）存活超过1年，无复发性胸腔积液迹象。
