类风湿关节炎：血清C反应蛋白及红细胞沉降率与放射学改变的关系
Rheumatoid arthritis: relation of serum C-reactive protein and erythrocyte sedimentation rates to radiographic changes.
作者信息
Amos R S, Constable T J, Crockson R A, Crockson A P, McConkey B
出版信息
Br Med J. 1977 Jan 22;1(6055):195-7. doi: 10.1136/bmj.1.6055.195.
Abstract
Serum C reactive protein (CRP) levels and erythrocyte sedimentation rates (ESR) were measured in 56 patients with rheumatoid arthritis. Radiographical damage, based on a count of erosions, was significantly more likely to occur when serum CRP and ESR were persistently raised, irrespective of the presence or absence of rheumatoid factor. Measurements of both CRP and ESR were more helpful than either alone, but CRP was probably the more informative. Serial measurements of CRP and ESR provide a reliable means of discriminating between drugs that provide symptomatic relief only and those with a more profound effect in rheumatoid arthritis.
摘要
对56例类风湿性关节炎患者测定了血清C反应蛋白（CRP）水平和红细胞沉降率（ESR）。基于侵蚀计数的影像学损伤，在血清CRP和ESR持续升高时显著更易发生，无论类风湿因子是否存在。CRP和ESR的测量比单独测量任一指标更有帮助，但CRP可能信息更多。CRP和ESR的系列测量提供了一种可靠的方法，可区分仅提供症状缓解的药物和对类风湿性关节炎有更显著疗效的药物。
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