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类风湿关节炎中红细胞沉降率与血清C反应蛋白之间的关系。

Relationship between erythrocyte sedimentation rate and serum C-reactive protein in rheumatoid arthritis.

作者信息

Walsh L, Davies P, McConkey B

出版信息

Ann Rheum Dis. 1979 Aug;38(4):362-3. doi: 10.1136/ard.38.4.362.

Abstract

Serum C-reactive protein (CRP) and the erythrocyte sedimentation rate (ESR) were compared in 241 patients with rheumatoid arthritis (RA). There was a positive linear correlation between the 2 measurements with a high degree of variability. Neither age nor duration of RA had a detectable influence. The relationship between CRP and ESR was, however, altered by treatment with gold, penicillamine, or high doses of prednisone. It is suggested that serum CRP is the more sensitive measurement, but that CRP and ESR do not have identical clinical significance.

摘要

对241例类风湿性关节炎(RA)患者的血清C反应蛋白(CRP)和红细胞沉降率(ESR)进行了比较。这两项测量之间存在正线性相关,但变异性很大。年龄和类风湿性关节炎病程均未产生可检测到的影响。然而,金制剂、青霉胺或高剂量泼尼松治疗会改变CRP和ESR之间的关系。研究表明,血清CRP是更敏感的测量指标,但CRP和ESR的临床意义并不相同。

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