Massarano A A, Hollis S, Devlin J, David T J
Department of Child Health, University of Manchester.
Arch Dis Child. 1993 May;68(5):677-9. doi: 10.1136/adc.68.5.677.
Growth was studied in 68 children aged 2-12 years with atopic eczema. Height SD scores were significantly correlated with the surface area of skin affected by eczema. The mean height of 41 patients with less than 50% of their skin surface affected (group I) was normal (mean SD score -0.11). The 27 children with more than 50% of their skin affected (group II) were significantly shorter (SD score -0.83) and were also short allowing for their parental target height. The predicted heights were also normal in group I but were lower than expected in group II. Regression analysis suggested that height was most dependent on parental height. The extent of the disease had a significant additional effect, whereas dietary treatment and treatment with topical steroids had only marginal additional effects. The growth of children with eczema affecting less than 50% of the skin surface area appears to be normal, and impaired growth is confined to those with more extensive disease.
对68名2至12岁的特应性皮炎患儿的生长情况进行了研究。身高标准差分数与受湿疹影响的皮肤表面积显著相关。41名皮肤表面积受影响小于50%的患者(第一组)的平均身高正常(平均标准差分数为-0.11)。27名皮肤受影响超过50%的儿童(第二组)明显更矮(标准差分数为-0.83),并且相对于其父母的目标身高也偏矮。第一组的预测身高也正常,但第二组低于预期。回归分析表明,身高最依赖于父母身高。疾病程度有显著的额外影响,而饮食治疗和局部类固醇治疗只有轻微的额外影响。湿疹影响皮肤表面积小于50%的儿童生长似乎正常,生长受损仅限于那些病情更广泛的儿童。