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血液荧光计。

The hematofluorometer.

作者信息

Blumberg W E, Eisinger J, Lamola A A, Zuckerman D M

出版信息

Clin Chem. 1977 Feb;23(2 PT. 1):270-4.

PMID:832391
Abstract

A portable filter fluorometer, the hematofluorometer--which utilizes "front face" optics, internal standards, and digital computation capabilities--has been specifically designed for the rapid (approximately 5 s) assay of erythrocyte zinc protoporphyrin in unprocessed blood. A small (unmeasured) drop of blood, such as is obtained from a finger puncture, is placed on disposable cover slip and inserted in the sample holder of the instrument. The operator pushes the holder of the instrument. The operator pushes the holder, which also holds the permanent blank and standard, into the instrument. Zinc protoporphyrin concentration is automatically and instantaneously computed and the value is displayed on a digital readout as micrograms of zinc protoporphyrin per deciliter of blood for some standard hematocrit. No calibration adjustment need be performed by the operator. The hematofluorometer is designed for "field" use as well as for laboratory assays.

摘要

一种便携式滤光荧光计,即血液荧光计,它采用“前表面”光学系统、内标和数字计算功能,专门设计用于快速(约5秒)测定未经处理血液中的红细胞锌原卟啉。一小滴(未测量)血液,如通过手指穿刺获得的血液,放置在一次性盖玻片上,然后插入仪器的样品架中。操作人员将仪器的样品架推进去。操作人员将同时装有永久性空白对照和标准品的样品架推进仪器。锌原卟啉浓度会自动即时计算出来,数值以每分升血液中锌原卟啉的微克数形式显示在数字读数上,适用于某种标准血细胞比容。操作人员无需进行校准调整。血液荧光计既设计用于“现场”使用,也适用于实验室检测。

相似文献

1
The hematofluorometer.血液荧光计。
Clin Chem. 1977 Feb;23(2 PT. 1):270-4.
2
Zinc protoporphyrin level in blood determined by a portable hematofluorometer: a screening device for lead poisoning.便携式血液荧光计测定血锌原卟啉水平:一种铅中毒筛查设备。
J Lab Clin Med. 1977 Apr;89(4):712-23.
3
Measurement of near-normal concentrations of erythrocyte protoporphyrin with the hematofluorometer: influence of plasma on "front-surface illumination" assay.用血液荧光计测量接近正常浓度的红细胞原卟啉:血浆对“前表面照明”检测的影响。
Clin Chem. 1981 Jan;27(1):153-6.
4
Fluorometric determination of erythrocyte protoporphyrin in blood, a comparison between direct (hematofluorometric) and indirect (extraction) methods.血液中红细胞原卟啉的荧光测定:直接法(血液荧光测定法)与间接法(萃取法)的比较
Clin Chem. 1978 Sep;24(9):1515-7.
5
Zinc protoporphyrin in blood as a biological indicator of chronic lead intoxication.血液中的锌原卟啉作为慢性铅中毒的生物学指标。
J Environ Pathol Toxicol. 1978 Jul-Aug;1(6):897-910.
6
Simultaneous quantitation of zinc protoporphyrin and free protoporphyrin in erythrocytes by acetone extraction.通过丙酮萃取同时定量测定红细胞中的锌原卟啉和游离原卟啉。
Clin Chem. 1981 Feb;27(2):220-2.
7
Empirically determined lead-poisoning screening cutoff for the Protofluor-Z hematofluorometer.
Clin Chem. 1989 Oct;35(10):2104-7.
8
Quantitative assay of erythrocyte "free" and zinc-protoporphyrin: clinical and genetic studies.红细胞“游离”和锌原卟啉的定量测定:临床与遗传学研究
Int J Biochem. 1980;12(5-6):1053-7. doi: 10.1016/0020-711x(80)90212-8.
9
Effect of bias in hematofluorometer measurements of protoporphyrin in screening programs for lead poisoning.
Clin Chem. 1985 Mar;31(3):386-90.
10
Free erythrocyte protoporphyrin (FEP) I. Normal values for adults and evaluation of the hematofluorometer.游离红细胞原卟啉(FEP)I. 成人正常值及血液荧光计评估
Am J Clin Pathol. 1983 Jun;79(6):655-60. doi: 10.1093/ajcp/79.6.655.

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Non-invasive measurement of erythrocyte zinc protoporphyrin in children.儿童红细胞锌原卟啉的无创测量。
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Is Erythrocyte Protoporphyrin a Better Single Screening Test for Iron Deficiency Compared to Hemoglobin or Mean Cell Volume in Children and Women?与血红蛋白或平均红细胞体积相比,红细胞原卟啉对儿童和女性缺铁性贫血来说是更好的单一筛查检测方法吗?
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Evaluation of Low Blood Lead Levels and Its Association with Oxidative Stress in Pregnant Anemic Women: A Comparative Prospective Study.低血铅水平及其与妊娠贫血女性氧化应激的关联评估:一项比较性前瞻性研究。
Indian J Clin Biochem. 2012 Jul;27(3):246-52. doi: 10.1007/s12291-012-0202-2. Epub 2012 Mar 29.
6
Impact of chronic lead exposure on selected biological markers.慢性铅暴露对选定生物标志物的影响。
Indian J Clin Biochem. 2012 Jan;27(1):83-9. doi: 10.1007/s12291-011-0163-x. Epub 2011 Sep 22.
7
Screening for lead poisoning in urban school children of southern India using capillary and venous blood samples.使用毛细血管血样和静脉血样对印度南部城市学童进行铅中毒筛查。
Indian J Clin Biochem. 2002 Jan;17(1):1-4. doi: 10.1007/BF02867932.
8
The free erythrocyte protoporphyrin assay in monitoring lead-exposed workers. Comparison of two fluorometric methods.游离红细胞原卟啉检测在铅接触工人监测中的应用。两种荧光测定法的比较。
Int Arch Occup Environ Health. 1980 Jan;45(1):35-48. doi: 10.1007/BF00378094.
9
Fluorometric assay of erythrocyte protoporphyrin: simple screening test for lead poisoning and iron deficiency.红细胞原卟啉的荧光测定:铅中毒和缺铁的简易筛查试验。
Can Med Assoc J. 1982 Nov 1;127(9):860-2.
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Health status of cable splicers with low-level exposure to lead: results of a clinical survey.低水平铅暴露电缆接头工的健康状况:一项临床调查结果
Am J Public Health. 1980 Jul;70(7):697-700. doi: 10.2105/ajph.70.7.697.