• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

OXCHECK试验中心脏病危险因素的患病率:对初级保健筛查的意义。帝国癌症研究基金会OXCHECK研究小组。

Prevalence of risk factors for heart disease in OXCHECK trial: implications for screening in primary care. Imperial Cancer Research Fund OXCHECK Study Group.

出版信息

BMJ. 1991 May 4;302(6784):1057-60. doi: 10.1136/bmj.302.6784.1057.

DOI:10.1136/bmj.302.6784.1057
PMID:2036503
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1669692/
Abstract

OBJECTIVE

To describe the outcome of offering health checks systematically to a general practice adult population, in terms of age and sex specific prevalence of risk factors, follow up workload, and selective screening of cholesterol concentration.

DESIGN

Descriptive analysis of data obtained by postal questionnaire and by personal interview and clinical examination by a trained nurse.

SUBJECTS

2205 patients aged 35-64 who attended for a health check in 1989-90 from an invited random sample of 2777 patients from five urban general practices in Bedfordshire.

RESULTS

Overall, almost three quarters of patients (78% of men, 68% of women) needed specific advice or follow up. Smoking, a high fat diet, and being overweight (body mass index greater than or equal to 25 kg/m2) were common characteristics exhibited by 35%, 31%, and 55% respectively of men and 24%, 18%, and 48% of women. The total cholesterol concentration was greater than or equal to 6.5 mmol/l in 37% of patients and greater than or equal to 8 mmol/l in 8%. In terms of workload 13% needed dietary advice only, 15% needed only follow up of hyperlipidaemia or hypertension, and 9% needed advice on smoking only. A further 35% needed follow up for a combination of risk factors. The proportion of patients in whom cholesterol concentration would be measured if a selective screening policy were adopted would vary from 29% to 71%, according to different criteria, but (particularly in men) no combination would be much better than random testing as a means to detect patients with a total cholesterol concentration greater than or equal to 8 mmol/l.

CONCLUSIONS

If the entire adult population of a practice is offered health checks systematically the acceptance rate is lower and the follow up workload higher than previously understood. The resource implications depend on the age and sex of patients screened and the selective criteria adopted for cholesterol measurement. Health checks are only the beginning of a successful preventive programme--the challenge is to provide effective intervention and follow up.

摘要

目的

从危险因素的年龄和性别特异性患病率、随访工作量以及胆固醇浓度的选择性筛查方面,描述对普通执业成人人群系统性提供健康检查的结果。

设计

对通过邮政问卷、个人访谈以及由经过培训的护士进行临床检查所获得的数据进行描述性分析。

研究对象

1989 - 1990年期间,从贝德福德郡五个城市普通执业诊所邀请的2777名患者的随机样本中,2205名年龄在35 - 64岁之间前来进行健康检查的患者。

结果

总体而言,近四分之三的患者(78%的男性,68%的女性)需要特定建议或随访。吸烟、高脂肪饮食以及超重(体重指数大于或等于25kg/m²)是常见特征,分别有35%的男性、24%的女性,31%的男性、18%的女性以及55%的男性、48%的女性表现出这些特征。37%的患者总胆固醇浓度大于或等于6.5mmol/l,8%的患者大于或等于8mmol/l。在工作量方面,13%的患者仅需要饮食建议,15%的患者仅需要对高脂血症或高血压进行随访,9%的患者仅需要戒烟建议。另外35%的患者需要针对多种危险因素进行随访。如果采用选择性筛查策略,根据不同标准,测量胆固醇浓度的患者比例从29%到71%不等,但(尤其是在男性中)作为检测总胆固醇浓度大于或等于8mmol/l患者的手段,没有哪种组合比随机检测好很多。

结论

如果对执业机构的全体成年人群系统性提供健康检查,接受率低于此前的认知,随访工作量高于此前的认知。资源需求取决于筛查患者的年龄和性别以及用于胆固醇测量的选择标准。健康检查只是成功预防计划的开端——挑战在于提供有效的干预和随访。

相似文献

1
Prevalence of risk factors for heart disease in OXCHECK trial: implications for screening in primary care. Imperial Cancer Research Fund OXCHECK Study Group.OXCHECK试验中心脏病危险因素的患病率:对初级保健筛查的意义。帝国癌症研究基金会OXCHECK研究小组。
BMJ. 1991 May 4;302(6784):1057-60. doi: 10.1136/bmj.302.6784.1057.
2
Effectiveness of health checks conducted by nurses in primary care: results of the OXCHECK study after one year. Imperial Cancer Research Fund OXCHECK Study Group.初级保健中护士进行健康检查的效果:OXCHECK研究一年后的结果。帝国癌症研究基金会OXCHECK研究小组。
BMJ. 1994 Jan 29;308(6924):308-12.
3
Effectiveness of health checks conducted by nurses in primary care: final results of the OXCHECK study. Imperial Cancer Research Fund OXCHECK Study Group.初级保健中护士进行健康检查的有效性:OXCHECK研究的最终结果。帝国癌症研究基金会OXCHECK研究小组。
BMJ. 1995 Apr 29;310(6987):1099-104.
4
Costs and cost effectiveness of health checks conducted by nurses in primary care: the Oxcheck study.初级保健中护士进行健康检查的成本及成本效益:Oxcheck研究
BMJ. 1996 May 18;312(7041):1265-8. doi: 10.1136/bmj.312.7041.1265.
5
Lifestyle advice in general practice: rates recalled by patients.全科医疗中的生活方式建议:患者回忆的比例
BMJ. 1992 Oct 10;305(6858):871-4. doi: 10.1136/bmj.305.6858.871.
6
Health checks in general practice: another example of inverse care?全科医疗中的健康检查:逆向医疗的又一实例?
BMJ. 1990 Apr 28;300(6732):1115-8. doi: 10.1136/bmj.300.6732.1115.
7
British family heart study: its design and method, and prevalence of cardiovascular risk factors.英国家庭心脏研究:其设计与方法以及心血管危险因素的患病率。
Br J Gen Pract. 1994 Feb;44(379):62-7.
8
9
Effectiveness of programme for reducing cardiovascular risk for men in one general practice.一项全科医疗中降低男性心血管疾病风险项目的成效
BMJ. 1993 Jun 19;306(6893):1652-6. doi: 10.1136/bmj.306.6893.1652.
10
The impact of health care advice given in primary care on cardiovascular risk. CELL Study Group.初级保健中提供的医疗保健建议对心血管风险的影响。CELL研究小组。
BMJ. 1995 Apr 29;310(6987):1105-9. doi: 10.1136/bmj.310.6987.1105.

引用本文的文献

1
Copy number amplification of TTPAL promotes cholesterol biosynthesis and esophageal squamous cell carcinoma progression via elevating NSUN2-mediated m5C modification of SREBP2 mRNA.TTPAL的拷贝数扩增通过提高NSUN2介导的SREBP2 mRNA的m5C修饰促进胆固醇生物合成和食管鳞状细胞癌进展。
J Exp Clin Cancer Res. 2025 Jul 26;44(1):220. doi: 10.1186/s13046-025-03483-8.
2
General health checks in adults for reducing morbidity and mortality from disease.成人进行一般健康检查以降低疾病的发病率和死亡率。
Cochrane Database Syst Rev. 2019 Jan 31;1(1):CD009009. doi: 10.1002/14651858.CD009009.pub3.
3
Systematic versus opportunistic risk assessment for the primary prevention of cardiovascular disease.心血管疾病一级预防的系统风险评估与机会性风险评估
Cochrane Database Syst Rev. 2016 Jan 29;2016(1):CD010411. doi: 10.1002/14651858.CD010411.pub2.
4
Screening for increased cardiometabolic risk in primary care: a systematic review.基层医疗中对心血管代谢风险增加的筛查:一项系统综述
Br J Gen Pract. 2014 Oct;64(627):e616-26. doi: 10.3399/bjgp14X681781.
5
Effectiveness of general practice-based health checks: a systematic review and meta-analysis.基于全科医疗的健康检查效果:系统评价和荟萃分析。
Br J Gen Pract. 2014 Jan;64(618):e47-53. doi: 10.3399/bjgp14X676456.
6
Availability and quality of coronary heart disease family history in primary care medical records: implications for cardiovascular risk assessment.初级保健医疗记录中冠心病家族史的可获取性和质量:对心血管风险评估的影响。
PLoS One. 2014 Jan 9;9(1):e81998. doi: 10.1371/journal.pone.0081998. eCollection 2014.
7
Pharmacogenetics of smoking cessation in general practice: results from the patch II and patch in practice trials.一般实践中戒烟的药物遗传学:贴片 II 及贴片实践试验的结果。
Nicotine Tob Res. 2011 Mar;13(3):157-67. doi: 10.1093/ntr/ntq246. Epub 2011 Jan 25.
8
Methods of the National Check Bus Project.国家校车检查项目的方法。
Soz Praventivmed. 2001;46(3):195-206. doi: 10.1007/BF01324256.
9
Screening for hypercholesterolaemia in primary care: randomised controlled trial of postal questionnaire appraising risk of coronary heart disease.基层医疗中高胆固醇血症的筛查:评估冠心病风险的邮政问卷随机对照试验。
BMJ. 1998 Apr 18;316(7139):1208-13. doi: 10.1136/bmj.316.7139.1208.
10
Three-yearly patient health checks.每三年进行一次患者健康检查。
Br J Gen Pract. 1992 Oct;42(363):439-40.

本文引用的文献

1
Facilitating prevention in primary care.在初级保健中促进预防工作。
Br Med J (Clin Res Ed). 1984 Dec 8;289(6458):1585-7. doi: 10.1136/bmj.289.6458.1585.
2
Blood lipid concentrations and other cardiovascular risk factors: distribution, prevalence, and detection in Britain.血脂浓度及其他心血管危险因素:在英国的分布、患病率及检测情况
Br Med J (Clin Res Ed). 1988 Jun 18;296(6638):1702-6. doi: 10.1136/bmj.296.6638.1702.
3
Narrowing the health gap between a deprived and an endowed community.缩小贫困社区与富裕社区之间的健康差距。
Br Med J (Clin Res Ed). 1988 Jan 16;296(6616):173-6. doi: 10.1136/bmj.296.6616.173.
4
Promoting prevention in primary care: controlled trial of low technology, low cost approach.在初级保健中促进预防:低技术、低成本方法的对照试验
Br Med J (Clin Res Ed). 1987 Apr 25;294(6579):1080-2. doi: 10.1136/bmj.294.6579.1080.
5
Prevention of cardiovascular disease in general practice: a proposed model.全科医疗中心血管疾病的预防:一个提议的模型。
Br Med J (Clin Res Ed). 1986 Jul 19;293(6540):177-80. doi: 10.1136/bmj.293.6540.177.
6
South Birmingham Coronary Prevention Project: a district approach to the prevention of heart disease.南伯明翰冠心病预防项目:一种预防心脏病的区域方法。
Community Med. 1989 May;11(2):90-6. doi: 10.1093/oxfordjournals.pubmed.a042464.
7
How-often-that-high graphs of serum cholesterol. Findings from the Scottish Heart Health and Scottish MONICA studies.血清胆固醇水平过高的情况有多常见。来自苏格兰心脏健康研究和苏格兰MONICA研究的结果。
Lancet. 1989 Mar 11;1(8637):540-2. doi: 10.1016/s0140-6736(89)90077-9.
8
Randomized controlled trial of anti-smoking advice by nurses in general practice.全科医疗中护士提供戒烟建议的随机对照试验。
J R Coll Gen Pract. 1989 Jul;39(324):273-6.
9
Cholesterol screening programmes: how much potential benefit?胆固醇筛查项目:潜在益处有多少?
BMJ. 1989 Sep 2;299(6699):606-7. doi: 10.1136/bmj.299.6699.606.
10
Would primary health care workers give appropriate dietary advice after cholesterol screening?初级卫生保健工作者在胆固醇筛查后会给出恰当的饮食建议吗?
BMJ. 1989 Jun 17;298(6688):1620-2. doi: 10.1136/bmj.298.6688.1620.