Lipman T H
Nursing of Children Division, University of Pennsylvania School of Nursing, Philadelphia.
Diabetes Care. 1993 Jun;16(6):922-5. doi: 10.2337/diacare.16.6.922.
To determine the epidemiology of type I diabetes in children in Philadelphia, particularly with respect to racial differences.
This is a descriptive epidemiological study using a retrospective population-based registry in Philadelphia, Pennsylvania, a city with large white, black, and Hispanic populations. All hospitals in Philadelphia that admit children were identified. All charts meeting the following criteria were reviewed: 1) newly diagnosed IDDM, 2) 0-14 yr of age, 3) residing in Philadelphia at the time of diagnosis, and 4) diagnosed from 1 January 1985 to 31 December 1989. Standard IDDM registry data were abstracted from the charts. Ascertainment of the completeness of the hospital registry was validated by two secondary sources: 1) diabetes camp records, 2) Philadelphia School District data.
A total of 215 cases were identified, and the combined hospital, camp, and school registry was determined to be 93% complete. The overall age-adjusted incidence rate in Philadelphia was 13.4/100,000/yr. The highest incidence rate was in Hispanics (15.16), followed by whites (13.31), and blacks (10.95).
The incidence of IDDM in Philadelphia is similar to what has been found in other U.S. registries. The unexpected finding was that the incidence in the Puerto Rican Hispanic population was the highest in the city. This is the first data reported on this population, and more studies are needed to elucidate the genetic and environmental causes of this high incidence of IDDM.
确定费城儿童1型糖尿病的流行病学情况，尤其是种族差异方面。
这是一项描述性流行病学研究，采用宾夕法尼亚州费城基于人群的回顾性登记系统，该市有大量白人、黑人和西班牙裔人口。确定了费城所有收治儿童的医院。对所有符合以下标准的病历进行审查：1）新诊断的胰岛素依赖型糖尿病（IDDM）；2）年龄在0至14岁；3）诊断时居住在费城；4）1985年1月1日至1989年12月31日期间确诊。从病历中提取标准的IDDM登记数据。通过两个二级来源验证医院登记的完整性：1）糖尿病营地记录；2）费城学区数据。
共确定215例病例，医院、营地和学校登记系统合并后的完整性为93%。费城总体年龄调整发病率为每年13.4/10万。发病率最高的是西班牙裔（15.16），其次是白人（13.31）和黑人（10.95）。
费城IDDM的发病率与美国其他登记系统的结果相似。意外发现是波多黎各西班牙裔人群的发病率在该市最高。这是关于该人群的首次数据报告，需要更多研究来阐明IDDM高发病率的遗传和环境原因。
