Sparrow J M, McLeod B K, Smith T D, Birch M K, Rosenthal A R
Department of Ophthalmology, University of Bristol, Bristol Eye Hospital, UK.
Eye (Lond). 1993;7 ( Pt 1):158-63. doi: 10.1038/eye.1993.34.
A total population study of the ocular status of all known non-insulin-treated diabetic patients resident in the English town of Melton Mowbray has been conducted. The population prevalence of non-insulin-treated diabetes in the town was 6.7/1000. There were 215 patients in the target population, with 65% of the resident survivors participating in the study. Further data on ocular status were gathered from hospital records, bringing the total percentage for whom some information on ocular status was available to 74%. Corrected Snellen acuity was 6/12 or better in 76% of patients and the over-all prevalence rate for any diabetic retinopathy was 52%, for proliferative retinopathy was 4%, and for maculopathy requiring treatment was 10%. In a multivariate analysis, risk factors for retinopathy and/or maculopathy included longer diabetic duration, female sex, higher blood pressure, the use of anti-hypertensive drugs and cigarette smoking.
对居住在英国梅尔顿莫布雷镇的所有已知非胰岛素治疗糖尿病患者的眼部状况进行了一项总体人群研究。该镇非胰岛素治疗糖尿病的人群患病率为6.7/1000。目标人群中有215名患者，65%的常住幸存者参与了研究。从医院记录中收集了更多关于眼部状况的数据，使可获得眼部状况某些信息的患者总数比例达到74%。76%的患者矫正视力为6/12或更好，任何糖尿病视网膜病变的总体患病率为52%，增殖性视网膜病变为4%，需要治疗的黄斑病变为10%。在多变量分析中，视网膜病变和/或黄斑病变的危险因素包括糖尿病病程较长、女性、血压较高、使用抗高血压药物和吸烟。
