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帕金森病中的言语冻结:通过电磁关节造影术对口腔面部运动进行运动学分析

Speech freezing in Parkinson's disease: a kinematic analysis of orofacial movements by means of electromagnetic articulography.

作者信息

Ackermann H, Gröne B F, Hoch G, Schönle P W

机构信息

Department of Neurology, University of Tübingen, FRG.

出版信息

Folia Phoniatr (Basel). 1993;45(2):84-9. doi: 10.1159/000266222.

DOI:10.1159/000266222
PMID:8325574
Abstract

Kinematic recordings of orofacial movements by means of electromagnetic articulography were performed in an akinetic-rigid Parkinsonian patient presenting with intermittent speech freezing in diadochokinesis tasks (rapid repetitions of the syllable /ta/). During freezing periods the patient produced a sustained /a/ instead of the required consonant-vowel sequences. The underlying articulatory trajectories were characterized by repetition rates amounting to 8-10 Hz concomitant with reduced movement amplitudes. Obviously, the undershooting of articulatory gestures failed to establish a sufficient occlusion of the vocal tract giving rise to the perceived speech freezing. In contrast, preserved diadochokinesis occurred at frequencies of 4-6 Hz. Most probably, the increased articulatory repetition rate reflects a pacing of orofacial movements by released tremor oscillations. Due to slowing of articulatory movements spastic dysarthrics can also present with missing syllabic modulation during oral diadochokinesis. The results of the articulographic recordings demonstrate the different pathophysiology of Parkinsonian freezing.

摘要

通过电磁关节造影术对口面部运动进行运动学记录,该记录针对一名患有运动不能-强直型帕金森病的患者,该患者在连续重复运动任务(音节/ta/的快速重复)中出现间歇性言语冻结。在冻结期,患者发出持续的/a/音,而不是所需的辅音-元音序列。潜在的发音轨迹的特征是重复率达8-10赫兹,同时运动幅度减小。显然,发音手势的动作不足未能建立起足够的声道闭塞,从而导致了所感知到的言语冻结。相比之下,在4-6赫兹的频率下出现了保留的连续重复运动。很可能,发音重复率的增加反映了由释放的震颤振荡引起的口面部运动的节奏。由于发音运动减慢,痉挛性构音障碍患者在口腔连续重复运动时也可能出现音节调制缺失。关节造影记录的结果证明了帕金森病冻结的不同病理生理学。

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