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前列腺素E2和去氧肾上腺素对人肾上腺儿茶酚胺体外释放的抑制作用。

Inhibition by PGE2 and by phenylephrine of catecholamine release from human adrenal in vitro.

作者信息

Boonyaviroj P, Gutman Y

出版信息

Eur J Pharmacol. 1977 Jan 7;41(1):73-5. doi: 10.1016/0014-2999(77)90373-9.

Abstract

The release of catecholamines from human adrenal was studied by in vitro incubation of slices. Catecholamine release was significantly inhibited by the addition of either phenylephrine (10(-5) M) or PGE2 (10(-7) M) to the incubation medium. The similarity of these modulating actions to those found in rat adrenal is discussed.

摘要

通过切片的体外孵育研究了人肾上腺中儿茶酚胺的释放。向孵育培养基中添加去氧肾上腺素(10⁻⁵ M)或前列腺素E2(10⁻⁷ M)可显著抑制儿茶酚胺的释放。讨论了这些调节作用与在大鼠肾上腺中发现的调节作用的相似性。

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