Eberlein T J, Crespo L D, Smith B L, Hergrueter C A, Douville L, Eriksson E
Division of Surgical Oncology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Ann Surg. 1993 Jul;218(1):29-36. doi: 10.1097/00000658-199307000-00006.
The authors prospectively studied the impact of immediate breast reconstruction on patients undergoing mastectomy.
Despite the advocation of a breast-conserving approach to the treatment of breast cancer, many women continue to medically require or choose mastectomy for the treatment of breast cancer. In recent years, immediate breast reconstruction has become an alternative to either mastectomy alone or to delayed reconstruction.
A prospective database of 216 patients who underwent mastectomy with immediate reconstruction was established. In this series, 94 procedures involved implants or tissue expanders, and 124 tissue transfers were performed.
The overall complication rate was 15.3%; only 9% of patients who underwent autologous tissue transfers required secondary procedures. When implants were performed, the overall rate of prosthetic loss was 8%. The majority of patients (n = 101) underwent transverse rectus abdominis musculocutaneous (TRAM) flaps. Twenty-six of the 38 (17.5%) patients who required transfusion were from this group. Partial flap losses in this group (7%) were correlated to a history of heavy smoking. With a median follow-up of 33.2 months, only two patients had recurred locally. According to patient opinion, autologous tissue transfers resulted in a statistically better cosmetic result.
Immediate reconstruction can be performed safely and with excellent cosmetic results.
作者前瞻性地研究了即刻乳房重建对接受乳房切除术患者的影响。
尽管提倡采用保乳方法治疗乳腺癌,但许多女性在医学上仍需要或选择乳房切除术来治疗乳腺癌。近年来,即刻乳房重建已成为单纯乳房切除术或延迟重建之外的另一种选择。
建立了一个包含216例接受即刻重建乳房切除术患者的前瞻性数据库。在该系列中,94例手术涉及植入物或组织扩张器,124例进行了组织移植。
总体并发症发生率为15.3%;接受自体组织移植的患者中只有9%需要二次手术。进行植入物手术时,假体丢失的总体发生率为8%。大多数患者(n = 101)接受了腹直肌肌皮瓣(TRAM)移植。38例(17.5%)需要输血的患者中有26例来自该组。该组部分皮瓣丢失(7%)与重度吸烟史相关。中位随访33.2个月,仅2例患者出现局部复发。根据患者的意见,自体组织移植在统计学上产生了更好的美容效果。
即刻重建可以安全地进行,并且美容效果极佳。