• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

对两种易患传染性海绵状脑病的羚羊的朊蛋白进行序列分析。

Sequence analysis of the PrP protein from two species of antelope susceptible to transmissible spongiform encephalopathy.

作者信息

Poidinger M, Kirkwood J, Almond W

机构信息

Department of Microbiology, School of Animal and Microbial Sciences, University of Reading, U.K.

出版信息

Arch Virol. 1993;131(1-2):193-9. doi: 10.1007/BF01379091.

DOI:10.1007/BF01379091
PMID:8328913
Abstract

The sequence of the coding regions of the PrP genes of the Arabian oryx and greater kudu have been determined and compared with the related sheep and bovine PrP gene sequences. The oryx gene sequence was found to be very closely related to that of the sheep, encoding just one amino acid difference. The greater kudu gene sequence was found to be more closely related to the bovine, encoding four amino acid differences. The possible influence that the gene sequences have on the transmission of spongiform encephalopathy to these antelope species is discussed.

摘要

已确定阿拉伯羚羊和大林羚PrP基因编码区的序列,并与相关的绵羊和牛PrP基因序列进行了比较。发现羚羊基因序列与绵羊的基因序列非常接近,仅编码一个氨基酸差异。发现大林羚基因序列与牛的基因序列关系更密切,编码四个氨基酸差异。讨论了基因序列对海绵状脑病向这些羚羊物种传播可能产生的影响。

相似文献

1
Sequence analysis of the PrP protein from two species of antelope susceptible to transmissible spongiform encephalopathy.对两种易患传染性海绵状脑病的羚羊的朊蛋白进行序列分析。
Arch Virol. 1993;131(1-2):193-9. doi: 10.1007/BF01379091.
2
Direct sequencing of PCR amplified pig PrP genes.猪朊蛋白基因PCR扩增产物的直接测序
Biochim Biophys Acta. 1995 Apr 24;1270(2-3):211-4. doi: 10.1016/0925-4439(95)00041-2.
3
Species-specificity of a panel of prion protein antibodies for the immunohistochemical study of animal and human prion diseases.一组朊病毒蛋白抗体在动物和人类朊病毒病免疫组织化学研究中的物种特异性。
J Comp Pathol. 2007 Jan;136(1):9-17. doi: 10.1016/j.jcpa.2006.09.002. Epub 2007 Jan 31.
4
Prion protein alleles showing a protective effect on the susceptibility of sheep to scrapie and bovine spongiform encephalopathy.对绵羊感染羊瘙痒病和牛海绵状脑病的易感性具有保护作用的朊病毒蛋白等位基因。
J Virol. 2007 Jul;81(13):7306-9. doi: 10.1128/JVI.02880-06. Epub 2007 Apr 18.
5
Prion encephalopathies of animals and humans.动物和人类的朊病毒脑病
Dev Biol Stand. 1993;80:31-44.
6
Evidence of a molecular barrier limiting susceptibility of humans, cattle and sheep to chronic wasting disease.存在一种分子屏障限制人类、牛和羊对慢性消耗病易感性的证据。
EMBO J. 2000 Sep 1;19(17):4425-30. doi: 10.1093/emboj/19.17.4425.
7
Comparative analysis of the prion protein open reading frame nucleotide sequences of two wild ruminants, the moufflon and golden takin.两种野生反刍动物摩弗伦羊和秦岭羚牛朊病毒蛋白开放阅读框核苷酸序列的比较分析
Intervirology. 2001;44(6):359-63. doi: 10.1159/000050072.
8
Molecular cloning and sequence analysis of prion protein gene in Xiji donkey in China.中国宁夏西吉驴朊蛋白基因的克隆与序列分析。
Gene. 2013 Oct 25;529(2):345-50. doi: 10.1016/j.gene.2013.08.019. Epub 2013 Aug 15.
9
Immunologic and molecular biologic studies of prion proteins in bovine spongiform encephalopathy.牛海绵状脑病中朊病毒蛋白的免疫学和分子生物学研究。
J Infect Dis. 1993 Mar;167(3):602-13. doi: 10.1093/infdis/167.3.602.
10
PrP genetics in ruminant transmissible spongiform encephalopathies.反刍动物传染性海绵状脑病中的朊蛋白基因学
Vet Res. 2008 Jul-Aug;39(4):30. doi: 10.1051/vetres:2008010. Epub 2008 Feb 15.

引用本文的文献

1
Prions and related neurological diseases.朊病毒与相关神经疾病
Mol Aspects Med. 1994;15(3):195-291. doi: 10.1016/0098-2997(94)90042-6.

本文引用的文献

1
Transmissible spongiform encephalopathy in greater kudu (Tragelaphus strepsiceros).大羚羊(Tragelaphus strepsiceros)的传染性海绵状脑病
Vet Rec. 1993 Jan 16;132(3):68. doi: 10.1136/vr.132.3.68-a.
2
Prions: novel infectious pathogens.朊病毒:新型传染性病原体。
Adv Virus Res. 1984;29:1-56. doi: 10.1016/s0065-3527(08)60404-2.
3
Genetic control of scrapie: incubation period and plaque formation in I mice.羊瘙痒病的遗传控制:I型小鼠的潜伏期和斑块形成
J Gen Virol. 1987 Feb;68 ( Pt 2):401-7. doi: 10.1099/0022-1317-68-2-401.
4
Fibrils from brains of cows with new cattle disease contain scrapie-associated protein.患有新型牛病的奶牛大脑中的原纤维含有与羊瘙痒病相关的蛋白质。
Nature. 1988 Nov 24;336(6197):390-2. doi: 10.1038/336390a0.
5
Distinct prion proteins in short and long scrapie incubation period mice.
Cell. 1987 Nov 20;51(4):651-62. doi: 10.1016/0092-8674(87)90134-6.
6
Pro----leu change at position 102 of prion protein is the most common but not the sole mutation related to Gerstmann-Sträussler syndrome.朊病毒蛋白第102位的脯氨酸-亮氨酸改变是与格斯特曼-施特劳斯勒综合征相关的最常见但并非唯一的突变。
Biochem Biophys Res Commun. 1989 Sep 15;163(2):974-9. doi: 10.1016/0006-291x(89)92317-6.
7
Linkage of the gene for the scrapie-associated fibril protein (PrP) to the Sip gene in Cheviot sheep.在切维厄特羊中,瘙痒病相关纤维蛋白(PrP)基因与Sip基因的连锁关系。
Vet Rec. 1989 Apr 8;124(14):364-6. doi: 10.1136/vr.124.14.364.
8
Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome.一种朊病毒蛋白错义变体与格斯特曼-施特劳斯勒综合征的关联。
Nature. 1989 Mar 23;338(6213):342-5. doi: 10.1038/338342a0.
9
Insertion in prion protein gene in familial Creutzfeldt-Jakob disease.家族性克雅氏病中朊蛋白基因的插入
Lancet. 1989 Jan 7;1(8628):51-2. doi: 10.1016/s0140-6736(89)91713-3.
10
Spongiform encephalopathy in an arabian oryx (Oryx leucoryx) and a greater kudu (Tragelaphus strepsiceros).阿拉伯大羚羊(白长角羚)和大林羚(扭角林羚)的海绵状脑病。
Vet Rec. 1990 Oct 27;127(17):418-20.