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49例脊髓减压病中严重程度、吸氧再压缩时间及再次治疗对预后的影响

Effect of severity, time to recompression with oxygen, and re-treatment on outcome in forty-nine cases of spinal cord decompression sickness.

作者信息

Ball R

机构信息

Naval Medical Research Institute, Bethesda, Maryland 20889-5055.

出版信息

Undersea Hyperb Med. 1993 Jun;20(2):133-45.

PMID:8329940
Abstract

For systematic study of the effects of clinical severity, time to recompression with oxygen, and re-treatment on outcome from spinal cord DCS, case records from the recompression chamber at the U.S. Naval Station Subic Bay were reviewed. Forty-nine cases of spinal cord DCS were classified using a numerical severity index and time to recompression with oxygen. Cases were divided by initial severity into mild, moderate, and severe groups and by time to recompression with oxygen into less than 12-h, 12-24-h, and greater than 24-h groups. Re-treatment effect was analyzed by severity after the first treatment and by the depth of the re-treatment table used. Severity after all treatment is strongly correlated with initial severity (r = 0.88) and moderately correlated with time to recompression with oxygen (r = 0.58). Response to treatment is significantly different among initial severity groups (P < 0.001). Delay to treatment worsens outcome for severely injured divers (P = 0.008). Residual severity after all treatments is highly correlated with severity after the first treatment (r = 0.97). There is no difference in re-treatment outcome by groups defined by severity after the first treatment or by 60- or 45-ft re-treatment tables.

摘要

为了系统研究临床严重程度、吸氧后再压缩时间以及再治疗对脊髓减压病(DCS)预后的影响,我们回顾了美国苏比克湾海军基地减压舱的病例记录。49例脊髓DCS病例根据数值严重程度指数和吸氧后再压缩时间进行分类。病例按初始严重程度分为轻度、中度和重度组,按吸氧后再压缩时间分为小于12小时、12 - 24小时和大于24小时组。再治疗效果根据首次治疗后的严重程度以及所使用的再治疗表深度进行分析。所有治疗后的严重程度与初始严重程度高度相关(r = 0.88),与吸氧后再压缩时间中度相关(r = 0.58)。初始严重程度组之间的治疗反应存在显著差异(P < 0.001)。治疗延迟会使重伤潜水员的预后恶化(P = 0.008)。所有治疗后的残余严重程度与首次治疗后的严重程度高度相关(r = 0.97)。根据首次治疗后的严重程度或60英尺或45英尺再治疗表定义的组,再治疗结果没有差异。

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