Yoffe N, Berger Y, Peled R, Lavie P
Sleep Laboratory, Technion Faculty of Medicine, Carmel Hospital, Haifa.
Harefuah. 1993 Apr 15;124(8):469-72, 527.
38 patients with obstructive sleep apnea syndrome underwent automated ambulatory 24-hour blood pressure monitoring. Systolic, diastolic and mean pressure values were significantly correlated with the apnea index (AI) during sleep, as well as during wakefulness. A significant negative correlation was found between minimal arterial O2 saturation in sleep and diastolic blood pressure values during waking hours. The contribution of the AI to blood pressure during sleep and wakefulness was significant, while the contribution of body mass index (BMI) was negligible. These results support the causal relationship between the severity of sleep apnea syndrome and systemic hypertension, independent of BMI.
38例阻塞性睡眠呼吸暂停综合征患者接受了自动动态24小时血压监测。收缩压、舒张压和平均血压值与睡眠期间以及清醒期间的呼吸暂停指数（AI）显著相关。睡眠期间最低动脉血氧饱和度与清醒时舒张压值之间存在显著负相关。睡眠和清醒期间AI对血压的影响显著，而体重指数（BMI）的影响可忽略不计。这些结果支持睡眠呼吸暂停综合征严重程度与系统性高血压之间的因果关系，且独立于BMI。
