Suppr超能文献

血液单核细胞表面黏附后,粗面内质网内过氧化物酶反应性的出现。

Appearance of peroxidase reactivity within the rough endoplasmic reticulum of blood monocytes after surface adherence.

作者信息

Bodel P T, Nichols B A, Bainton D F

出版信息

J Exp Med. 1977 Feb 1;145(2):264-74. doi: 10.1084/jem.145.2.264.

Abstract

Rabbit blood monocytes, which contain no cytochemically demonstrable peroxidase, develop peroxidatic activity in the RER and perinuclear cisternae within 2 h after adherence to serum- or fibrin-coated surfaces. A similar reactivity appears in surface-adherent human and rat blood monocytes. In both localization and characteristics, this enzyme reactivity in monocytes resembles that normally seen in the resident peritoneal macrophages of the rabbit, as well as in several types of tissue macrophages in other species. Thus this observation supports the concept, presently based on the kinetic data of other investigators, that blood monocytes are the precursors of such cells. Moreover, the appearance of new enzyme activity after adherence may reflect alterations in cellular metabolism resulting from plasma membrane:surface interactions.

摘要

兔血单核细胞不含细胞化学可显示的过氧化物酶,在黏附于血清或纤维蛋白包被的表面后2小时内,其粗面内质网和核周池会产生过氧化物酶活性。表面黏附的人血和大鼠血单核细胞也出现类似反应。单核细胞中的这种酶反应性在定位和特征上与兔常驻腹膜巨噬细胞以及其他物种的几种组织巨噬细胞中通常所见的相似。因此,这一观察结果支持了目前基于其他研究者动力学数据的概念,即血单核细胞是这类细胞的前体。此外,黏附后新酶活性的出现可能反映了质膜与表面相互作用导致的细胞代谢变化。

相似文献

5
Endogenous peroxidase activity in mononuclear phagocytes.单核吞噬细胞中的内源性过氧化物酶活性。
Prog Histochem Cytochem. 1984;15(2):1-58. doi: 10.1016/s0079-6336(84)80003-0.

引用本文的文献

本文引用的文献

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验