Papa F, Cruaud P, Luquin M, Thorel M F, Goh K S, David H L
Unité de la Tuberculose et des Mycobactéries, Institut Pasteur, Paris, France.
Res Microbiol. 1993 Feb;144(2):91-9. doi: 10.1016/0923-2508(93)90021-s.
Two major highly polar antigenic glycolipids were isolated from recent isolates of Mycobacterium tuberculosis from a wide range of geographical origins. The occurrence of these polar glycolipids was demonstrated by isolation, purification and chromatographic characterization and/or serological procedures in 12 strains. Based on their chromatographic properties, these polar glycolipids belong to the lipooligosaccharide family. Preliminary data on the use of these newly described antigens in the serodiagnosis of tuberculosis is presented.
从来自广泛地理区域的结核分枝杆菌近期分离株中分离出两种主要的高极性抗原性糖脂。通过对12株菌株进行分离、纯化、色谱表征和/或血清学检测，证实了这些极性糖脂的存在。基于其色谱特性，这些极性糖脂属于脂寡糖家族。文中还给出了关于这些新描述的抗原在结核病血清诊断中应用的初步数据。
