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杜克大学衰老纵向研究

Duke University Longitudinal Studies of Aging.

作者信息

Busse E W

机构信息

North Carolina Institute of Medicine, Durham.

出版信息

Z Gerontol. 1993 May-Jun;26(3):123-8.

PMID:8337904
Abstract

The Duke Longitudinal Studies of Aging were preceded by a research project supported by the National Institutes of Health and entitled "The Effects of Aging upon the Central Nervous System: A Physiological and Psychological Approach." These earlier studies formed a solid basis for designing and carrying out the two Duke Longitudinal Studies. The Duke longitudinal interdisciplinary research team existed between 1955 and 1980. The first longitudinal study of "normal aging" began in 1955. The subjects were 270 community residents and volunteers aged 60 to 90. Eleven rounds of complete examinations were carried out. The eleventh and final round occurred in 1976. The second Duke Longitudinal Study (also known as the "Adaptation Study") began in 1968 and ended in 1976. The research design was cross-sequential with 502 subjects 46 to 70 years of age. Numerous ancillary studies were conducted on both studies. Both studies included biomedical, psychological, and socioeconomic observations and evaluation procedures. All data are preserved and available for secondary analysis by qualified persons.

摘要

在开展杜克大学衰老纵向研究之前,有一个由美国国立卫生研究院支持的研究项目,名为“衰老对中枢神经系统的影响:生理和心理学方法”。这些早期研究为设计和开展两项杜克大学纵向研究奠定了坚实基础。杜克大学纵向跨学科研究团队存在于1955年至1980年之间。第一项关于“正常衰老”的纵向研究始于1955年。研究对象是270名年龄在60至90岁之间的社区居民和志愿者。进行了11轮全面检查。第11轮也是最后一轮检查于1976年进行。第二项杜克大学纵向研究(也称为“适应研究”)始于1968年,结束于1976年。研究设计采用交叉序列设计,有502名年龄在46至70岁之间的受试者。两项研究都进行了大量辅助研究。两项研究都包括生物医学、心理学和社会经济观察及评估程序。所有数据均已保存,可供有资质的人员进行二次分析。

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