系统性红斑狼疮伴IgG抗心磷脂抗体的严重视网膜病变。

Severe retinopathy in systemic lupus erythematosus associated with IgG anticardiolipin antibodies.

作者信息

Ravelli A, Di Fuccia G, Caporali R, Malvezzi F, Montecucco C, Martini A

机构信息

Clinica Pediatrica, Universita di Pavia, IRCCS S Matteo, Italy.

出版信息

Acta Paediatr. 1993 Jun-Jul;82(6-7):624-6. doi: 10.1111/j.1651-2227.1993.tb12774.x.

DOI:10.1111/j.1651-2227.1993.tb12774.x

PMID:8339008

Abstract

A six-year-old boy with systemic lupus erythematosus developed insidiously a monolateral serous retinal detachment leading to severe visual loss. Serial determinations of anticardiolipin antibodies showed the presence of IgG anticardiolipin antibodies only at the time of ocular involvement. This case underlines the need for regular ophthalmologic evaluation in children with active systemic lupus erythematosus and supports the previous hypothesis of a relationship between antiphospholipid antibodies and retinal involvement in systemic lupus erythematosus.

摘要

一名患有系统性红斑狼疮的六岁男孩不知不觉地出现了单侧浆液性视网膜脱离，导致严重视力丧失。抗心磷脂抗体的系列检测显示，仅在眼部受累时存在IgG抗心磷脂抗体。该病例强调了对患有活动性系统性红斑狼疮的儿童进行定期眼科评估的必要性，并支持了先前关于抗磷脂抗体与系统性红斑狼疮视网膜受累之间关系的假设。