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[逆行胰胆管造影术及内镜括约肌切开术治疗胆石症。外科领域的前瞻性评估]

[Retrograde cholangiopancreatography and endoscopic sphincterotomy for biliary lithiasis. Prospective evaluation in surgical circle].

作者信息

Lenriot J P, Le Neel J C, Hay J M, Jaeck D, Millat B, Fagniez P L

机构信息

Service de Chirurgie Viscérale et Digestive, Centre Hospitalier Général, Longjumeau.

出版信息

Gastroenterol Clin Biol. 1993;17(4):244-50.

PMID:8339882
Abstract

Between January 1982 and 1987, 772 consecutive endoscopic retrograde cholangiopancreatographic examinations (ERCP) were performed in 673 consecutive patients suspected of having biliary tract lithiasis (mean age: 62.1 +/- 18.2 years). Two hundred and thirty-two were emergency procedures (30%). Endoscopic sphincterotomy was performed for common bile duct stones (CBDS) in 257 cases (38.0%), of whom 143 (55.6%) had undergone previous cholecystectomy. In 17.2% of cases, ERCP was either a complete (7.8%) or partial (9.4%) failure. In 124 patients for whom microlithiasis was not identified by sonography and who underwent operation, sensitivity and specificity of ERCP was 70% and 87%, respectively. Of 266 patients in whom ES was attempted, 96.6% were achieved and the common bile duct was cleared of stones in 72% of cases. Nineteen percent of patients required two or more attempts at extraction. After ERCP without ES, mortality and morbidity rates were 0.96 and 3.6% respectively. After ES, complications followed in 12.1% of patients and 3.9% died. Mortality and morbidity directly related to ES were 3.1% and 11.3% respectively. The most common complications after ERCP were acute cholangitis and pancreatitis, whereas after ES, acute cholangitis was the most common complication, followed by hemorrhage and duodenocholechocal perforations. These complications occurred independently of age and previous cholecystectomy but was closely related to stone clearance (P < 0.05). Seventy-one patients (10.5%) required operation. Twenty-nine patients underwent emergency surgery for complications with a mortality rate of 17%. Forty-two patients underwent elective surgery for retained CBDS after ES without any mortality.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1982年1月至1987年期间,对673例疑有胆道结石的连续患者进行了772例连续的内镜逆行胰胆管造影检查(ERCP)(平均年龄:62.1±18.2岁)。232例为急诊手术(30%)。257例(38.0%)因胆总管结石(CBDS)行内镜括约肌切开术,其中143例(55.6%)曾接受过胆囊切除术。17.2%的病例中,ERCP检查完全失败(7.8%)或部分失败(9.4%)。124例超声未发现微结石且接受手术的患者中,ERCP的敏感性和特异性分别为70%和87%。在266例尝试内镜括约肌切开术(ES)的患者中,96.6%成功,72%的病例胆总管结石清除。19%的患者需要两次或更多次取石尝试。未行ES的ERCP术后,死亡率和发病率分别为0.96%和3.6%。ES术后,12.1%的患者出现并发症,3.9%死亡。与ES直接相关的死亡率和发病率分别为3.1%和11.3%。ERCP术后最常见的并发症是急性胆管炎和胰腺炎,而ES术后,急性胆管炎是最常见的并发症,其次是出血和十二指肠胆肠穿孔。这些并发症的发生与年龄和既往胆囊切除术无关,但与结石清除密切相关(P<0.05)。71例患者(10.5%)需要手术。29例患者因并发症接受急诊手术,死亡率为17%。42例患者在ES后因残留CBDS接受择期手术,无死亡病例。(摘要截短至250字)

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