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精神分裂症高危儿童的神经行为功能与社会行为

Neurobehavioral functioning and social behavior of children at risk for schizophrenia.

作者信息

Auerbach J G, Hans S, Marcus J

机构信息

JDC Institute of Mental Health and Behavioral Studies, Jerusalem.

出版信息

Isr J Psychiatry Relat Sci. 1993;30(1):40-9.

PMID:8340219
Abstract

The neurobehavioral functioning and social behavior of children with mentally ill and mentally healthy parents were examined. The children, 8 to 13 years of age, were assessed with a battery of neurobehavioral tests. The children's teachers rated their interpersonal behavior. Each of the families was rated on quality of childbearing environment. Children of schizophrenic parents performed more poorly on the neurobehavioral tests, in particular those assessing perceptual-cognitive functioning, than children of parents with other psychiatric disorders or with no history of mental illness. There were no group differences in aggressive behavior. Sons of schizophrenic parents were rated as more withdrawn than the other children in the study. The relationship between childrearing environment, neurobehavioral functioning, and social behavior was in the expected direction for the children of mentally healthy parents. An atypical pattern emerged for the offspring of mentally ill parents.

摘要

对父母患有精神疾病和父母精神健康的儿童的神经行为功能和社会行为进行了检查。这些8至13岁的儿童接受了一系列神经行为测试。孩子们的老师对他们的人际行为进行了评分。每个家庭都根据生育环境质量进行了评分。与患有其他精神疾病或无精神疾病史的父母的孩子相比,患有精神分裂症的父母的孩子在神经行为测试中表现更差,尤其是在评估感知认知功能的测试中。攻击行为方面没有组间差异。在该研究中,患有精神分裂症的父母的儿子被评为比其他孩子更孤僻。对于精神健康的父母的孩子,养育环境、神经行为功能和社会行为之间的关系符合预期方向。而患有精神疾病的父母的后代则出现了一种非典型模式。

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引用本文的文献

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Conceptualization of the liability for schizophrenia: clinical implications.精神分裂症责任的概念化:临床意义。
Dialogues Clin Neurosci. 1999 Dec;1(3):153-64. doi: 10.31887/DCNS.1999.1.3/mtsuang.
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Psychopathology in children of schizophrenics.精神分裂症患者子女的精神病理学。
Indian J Psychiatry. 2003 Apr;45(2):31-8.
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Toward a model of memory enhancement in schizophrenia: glucose administration and hippocampal function.迈向精神分裂症记忆增强模型:葡萄糖给药与海马体功能。
Schizophr Bull. 2008 Jan;34(1):93-108. doi: 10.1093/schbul/sbm041. Epub 2007 May 15.
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Avoidant personality disorder is a separable schizophrenia-spectrum personality disorder even when controlling for the presence of paranoid and schizotypal personality disorders The UCLA family study.回避型人格障碍是一种可分离的精神分裂症谱系人格障碍,即使在控制偏执型和分裂型人格障碍存在的情况下(加州大学洛杉矶分校家庭研究)。
Schizophr Res. 2007 Mar;91(1-3):192-9. doi: 10.1016/j.schres.2006.12.023. Epub 2007 Feb 15.